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纳米银敷料在糖尿病足治疗中的应用进展

Application Progress of Nano Silver Dressing in the Treatment of Diabetic Foot.

作者信息

Lin Huijing, BoLatai Alayi, Wu Na

机构信息

Department of Endocrinology, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, People' s Republic of China.

Student Affairs Department, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, People' s Republic of China.

出版信息

Diabetes Metab Syndr Obes. 2021 Oct 1;14:4145-4154. doi: 10.2147/DMSO.S330322. eCollection 2021.

Abstract

Diabetic foot is a serious infection of the lower limbs. It is caused by diabetic neuropathy and vascular disease. It is also the primary cause of disability and death in patients with severe diabetes, so prompt treatment is essential for positive outcomes. The clinical use of nano-silver dressings can be considered to further optimize the treatment process and improve the treatment efficacy in diabetic foot patients. Nano-silver dressings have a larger contact surface and a stronger bactericidal effect when compared to ordinary silver dressings. Besides, it can be disinfected repeatedly to better wound infection control and promote wound healing. The current article discusses the pathogenesis of diabetic foot, diabetic foot dressing treatment, the application of nanotechnology in diabetic foot treatment, the efficacy evaluation of different dressings, and the practical prospects of adopting nanotechnology in the treatment of diabetic foot.

摘要

糖尿病足是下肢的一种严重感染。它由糖尿病神经病变和血管疾病引起。它也是重度糖尿病患者致残和死亡的主要原因,因此及时治疗对于取得良好疗效至关重要。可以考虑临床使用纳米银敷料以进一步优化治疗过程并提高糖尿病足患者的治疗效果。与普通银敷料相比,纳米银敷料具有更大的接触面积和更强的杀菌效果。此外,它可以反复消毒,以更好地控制伤口感染并促进伤口愈合。本文讨论了糖尿病足的发病机制、糖尿病足敷料治疗、纳米技术在糖尿病足治疗中的应用、不同敷料的疗效评估以及采用纳米技术治疗糖尿病足的实际前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7908/8491782/c062787c1206/DMSO-14-4145-g0001.jpg

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