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慢性疼痛患者残疾的患病率及相关因素:一项观察性研究。

Prevalence and associated factors of disability in patients with chronic pain: An observational study.

机构信息

Department of Anesthesiology, Nara Medical University, Shijo-cho, Kashihara, Nara, Japan.

出版信息

Medicine (Baltimore). 2021 Oct 8;100(40):e27482. doi: 10.1097/MD.0000000000027482.

Abstract

The primary treatment goal of patients experiencing chronic pain has shifted from pain reduction to functional status improvement. However, the prevalence of disability and its associated factors in patients with chronic pain remain unknown.Individuals aged ≥50 years who visited the Pain Center at Nara Medical University with chronic pain from June 2019 to May 2020 were eligible for enrollment. Patients were asked to complete the Japanese version of the 12-item World Health Organization Disability Assessment Schedule 2.0. Patient demographics, pain intensity, level of catastrophizing, anxiety, depression, and exercise habits were assessed. Multivariate logistic regression analysis was used to identify the factors associated with disability.Of the 551 patients with a median age of 73 years, 51.5% experienced disability. Fixed factors such as age (odds ratio [OR], 1.03; 95% confidence interval [CI] 1.01-1.06, P = .002) and lumbar and lower limb pain (OR, 3.10; 95% CI, 1.83-5.24, P < .001) and some modifiable factors, including anxiety (OR, 2.06; 95% CI, 1.06-3.98, P = .03), depression (OR, 3.62; 95% CI, 1.92-6.82, P < .001), pain catastrophizer (OR, 2.94; 95% CI, 1.88-4.61, P < .001), numeric rating scale at the most painful site (OR, 1.29; 95% CI, 1.18-1.42, P < .001), exercise habits (walking (OR, 0.52; 95% CI, 0.33-0.83, P = .006) and working out (OR, 0.58; 95% CI, 0.34-0.99, P = .046), were found to be independently associated with disability.This cross-sectional study revealed a high prevalence of disability in patients with chronic pain and identified the factors associated with disability.

摘要

患有慢性疼痛的患者的主要治疗目标已经从减轻疼痛转变为改善功能状态。然而,慢性疼痛患者的残疾患病率及其相关因素仍不清楚。

2019 年 6 月至 2020 年 5 月,年龄≥50 岁的个体因慢性疼痛前往奈良医科大学疼痛中心就诊,符合入组条件。患者被要求完成日本版 12 项世界卫生组织残疾评估量表 2.0。评估患者的人口统计学特征、疼痛强度、灾难化程度、焦虑、抑郁和运动习惯。采用多变量逻辑回归分析确定与残疾相关的因素。

在 551 名中位年龄为 73 岁的患者中,51.5%有残疾。年龄(比值比[OR],1.03;95%置信区间[CI],1.01-1.06,P=0.002)和腰腿部疼痛(OR,3.10;95%CI,1.83-5.24,P<0.001)等固定因素以及一些可改变的因素,包括焦虑(OR,2.06;95%CI,1.06-3.98,P=0.03)、抑郁(OR,3.62;95%CI,1.92-6.82,P<0.001)、疼痛灾难化(OR,2.94;95%CI,1.88-4.61,P<0.001)、最痛部位的数字评分量表(OR,1.29;95%CI,1.18-1.42,P<0.001)和运动习惯(散步(OR,0.52;95%CI,0.33-0.83,P=0.006)和锻炼(OR,0.58;95%CI,0.34-0.99,P=0.046),与残疾独立相关。

这项横断面研究显示,慢性疼痛患者的残疾患病率较高,并确定了与残疾相关的因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0225/8500618/bed02033ab67/medi-100-e27482-g001.jpg

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