COVID-19 患者复发性 SARS-CoV-2 RNA 阳性和病毒持续排出：一例病例报告。
Recurrent SARS-CoV-2 RNA positivity and prolonged viral shedding in a patient with COVID-19: a case report.
机构信息
Department of Infectious Diseases, Huizhou Third People's Hospital, Guangzhou Medical University, Huizhou, 516000, China.
Department of Neurology, Huizhou Third People's Hospital, Guangzhou Medical University, Huizhou, 516000, China.
出版信息
BMC Infect Dis. 2021 Oct 18;21(1):1076. doi: 10.1186/s12879-021-06776-3.
BACKGROUND
The ongoing coronavirus disease 2019 (COVID-19) global pandemic caused by the SARS-CoV-2 virus remains a major threat to public health. At present, it is recommended that patients with known or suspected COVID-19 undergo quarantine or medical observation for 14 days. However, recurrent SARS-CoV-2 RNA positivity and prolonged viral shedding have been documented in convalescent COVID-19 patients, complicating efforts to control viral spread and ensure patient recovery.
CASE PRESENTATION
We report the case of a patient who experienced two recurrent episodes of SARS-CoV-2 RNA and IgM positivity and viral shedding over 60 days during hospitalization.
CONCLUSIONS
This case report demonstrates that relapses of SARS-CoV-2 RNA and IgM positivity may occur even after COVID-19 symptoms have resolved, possibly as a consequence of prolonged viral shedding rather than re-infection.
背景
由 SARS-CoV-2 病毒引起的持续的 2019 年冠状病毒病（COVID-19）全球大流行仍然是对公众健康的主要威胁。目前，建议已知或疑似 COVID-19 的患者进行 14 天的隔离或医学观察。然而，在康复的 COVID-19 患者中已经记录到反复的 SARS-CoV-2 RNA 阳性和病毒持续排出，这增加了控制病毒传播和确保患者康复的难度。
病例介绍
我们报告了一例患者在住院期间经历了两次 SARS-CoV-2 RNA 和 IgM 阳性和病毒排出超过 60 天的反复发作。
结论
本病例报告表明，即使 COVID-19 症状已经消退，SARS-CoV-2 RNA 和 IgM 阳性也可能复发，这可能是由于病毒持续排出而不是再感染所致。
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