Department of Clinical Studies, New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, 382 West Street Road, Kennett Square, PA 19348, USA.
Department of Clinical Studies, New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, 382 West Street Road, Kennett Square, PA 19348, USA.
Vet Clin North Am Equine Pract. 2021 Dec;37(3):657-668. doi: 10.1016/j.cveq.2021.08.002. Epub 2021 Oct 19.
Supporting limb laminitis (SLL) is a relatively frequent complication of painful limb conditions that alter normal weight-bearing patterns in horses. New evidence suggests that a lack of limb load cycling activity (normally associated with ambulation) interferes with normal perfusion of the lamellae in these cases, resulting in ischemia and dysfunction/death of cells critical to the mechanical function of the lamellae. Excessive weight-bearing load drives the progression to overt acute laminitis in the supporting limb. Monitoring and enhancement of limb load cycling activity are key strategies that may lead to successful prevention of SLL by ensuring adequate lamellar perfusion.
支持性肢蹄底溃疡(SLL)是一种较为常见的疼痛性肢蹄疾病的并发症,改变了马正常的负重模式。新的证据表明,缺乏肢蹄负重循环活动(通常与行走有关)会干扰这些情况下的蹄叶正常灌注,导致缺血和对蹄叶机械功能至关重要的细胞功能障碍/死亡。过度的负重会导致支持性肢蹄急性底溃疡的发展。监测和增强肢蹄负重循环活动是关键策略,通过确保足够的蹄叶灌注,可能有助于成功预防 SLL。