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结肠癌腋窝淋巴结转移负荷重的临床及超声特征

Clinical and ultrasound features correlated with a heavy axillary nodal tumor burden in colon cancer.

机构信息

Department of Ultrasound, Anhui Medical University Affiliated Hefei Hospital, Hefei Second People's Hospital, Guangde Road, Hefei 230011, Anhui, China.

Department of Ultrasound, Anhui Provincial Hospital Affiliated to Anhui Medical University (The First Affiliated Hospital of University of Science & Technology of China), Lujiang Road, Hefei 230001, Anhui, China.

出版信息

Future Oncol. 2021 Nov;17(32):4289-4297. doi: 10.2217/fon-2020-1029. Epub 2021 Oct 22.

Abstract

This study aimed to investigate the correlation between the pathologic and ultrasound (US) characteristics of colon cancer and the heavy axillary nodal burden. In total, 631 patients diagnosed with invasive colon cancer were recruited with ethical ratification. The unitary pathologic features correlated with heavy axillary lymph nodal burden included the age of patient (p = 0.035), tumor size (p = 0.001), lymph node metastasis (p = 0.001), lymphovascular invasion (p = 0.020) and pathology type (p = 0.012). The independent US characteristics correlated with heavy axillary nodal burden included posterior acoustic enhancement (p = 0.006). Heavy axillary nodal burden was correlated with tumor size, lymph node metastasis, lymphovascular invasion and pathology type. Tumor size, lymph node metastasis and posterior acoustic can be used to predict the axillary lymph node tumor burden.

摘要

本研究旨在探讨结肠癌的病理和超声(US)特征与腋窝淋巴结负荷过重之间的相关性。共招募了 631 名经病理诊断为浸润性结肠癌的患者,本研究经伦理批准。与腋窝淋巴结负荷过重相关的单一病理特征包括患者年龄(p=0.035)、肿瘤大小(p=0.001)、淋巴结转移(p=0.001)、淋巴管浸润(p=0.020)和病理类型(p=0.012)。与腋窝淋巴结负荷过重相关的独立 US 特征包括后方回声增强(p=0.006)。腋窝淋巴结负荷过重与肿瘤大小、淋巴结转移、淋巴管浸润和病理类型相关。肿瘤大小、淋巴结转移和后方回声可用于预测腋窝淋巴结肿瘤负荷。

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