School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200436, China.
Shanghai Key Laboratory for Veterinary and Biotechnology, Shanghai 200436, China.
Molecules. 2021 Oct 14;26(20):6205. doi: 10.3390/molecules26206205.
This work investigated the preparation, characterization, antioxidant, and anti-inflammation capacities of polyphenols (FVP) and fermented FVP (FFVP). The results revealed that the new syringic acid, accounting for 22.22%, was obtained after fermentation (FFVP). FFVP exhibits higher antioxidant and anti-inflammation activities than FVP, enhancing cell viability and phagocytosis, inhibiting the secretion of NO and ROS, and reducing the inflammatory response of RAW264.7 cells. This study revealed that FFVP provides a theoretical reference for in-depth study of its regulatory mechanisms and further development of functional antioxidants that are applicable in the food and health industry.
本研究旨在探讨多酚(FVP)及其发酵产物(FFVP)的制备、特性、抗氧化和抗炎能力。结果表明,发酵后得到了新的丁香酸,占 22.22%。FFVP 表现出比 FVP 更高的抗氧化和抗炎活性,可提高细胞活力和吞噬作用,抑制 NO 和 ROS 的分泌,减轻 RAW264.7 细胞的炎症反应。本研究为深入研究其调节机制以及进一步开发适用于食品和健康产业的功能性抗氧化剂提供了理论参考。