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核心结局指标中的生活质量评估:EADV 生活质量和患者导向结局工作组的立场声明。

Quality of life assessment in core outcome sets: A position statement of the EADV Task Force on Quality of Life and Patient Oriented Outcomes.

机构信息

Department of Dermatology and Venereology, National Medical University, Kiev, Ukraine.

Health, Medical, and Neuropsychology unit, Leiden University, Leiden, The Netherlands.

出版信息

J Eur Acad Dermatol Venereol. 2022 Jan;36(1):20-23. doi: 10.1111/jdv.17725. Epub 2021 Oct 23.

Abstract

Core outcome sets (COSs) are an agreed standardized collection of outcomes that should be measured and reported in all clinical trials for a specific clinical condition. Tsekhe aim of our position paper by the European Academy of Dermatology and Venereology (EADV) Task Force on Quality of Life and Patient Oriented Outcomes was to identify the challenges and Patient Oriented Outcomes advantages in the development of COSs within dermatological QoL research. Twelve EADV Task Force multidisciplinary team members presented a total of 101 items (51 advantages and 50 disadvantages). All participants considered that COS are beneficial for comparison between different studies, treatments, dermatological diseases, geographical location and ethnicities. In conclusion, the EADV Task Force on Quality of Life and Patient Oriented Outcomes has recognized the primacy of advantages of COS and deliberated that the disadvantages in COS are related to development process and use of COS.

摘要

核心结局集(COS)是一组经过临床医生认可的标准化结局指标,在针对某一特定临床情况的所有临床试验中都应该进行测量和报告。本研究旨在明确在皮肤病学 QoL 研究中开发 COS 的挑战和优势。欧洲皮肤病学会和性病学会(EADV)生活质量和患者导向结局工作组的 12 名多学科团队成员共提出了 101 项内容(51 项优势,50 项劣势)。所有参与者均认为 COS 有利于比较不同研究、治疗、皮肤病、地理位置和种族之间的差异。总之,EADV 生活质量和患者导向结局工作组认识到 COS 的优势是首要的,并认为 COS 的劣势与 COS 的开发过程和使用有关。

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