Northwestern Feinberg School of Medicine, Division of Vascular Surgery, Surgery Department, Chicago, Illinois.
Northwestern Feinberg School of Medicine, Division of Vascular Surgery, Surgery Department, Chicago, Illinois.
Ann Vasc Surg. 2022 Feb;79:91-99. doi: 10.1016/j.avsg.2021.08.033. Epub 2021 Oct 20.
Enhanced recovery after surgery (ERAS) programs provide a streamlined approach for expedient postoperative care of high-volume procedures. Endovascular aortic repair (EVAR) has become standard treatment for abdominal aortic aneurysms and implementation of an early recovery program is warranted. Postoperative urinary retention (POUR) remains a problem lending to longer hospital stays and patient discomfort. We aim to demonstrate the utility of monitored anesthetic care (MAC) plus local anesthesia as a modality to minimize urinary retention following EVAR.
Single-center retrospective review from January 2017 to March 2020 of all patients undergoing standard elective EVAR under general anesthesia or MAC anesthesia. Local anesthetic at vessel access sites was used in all patients under MAC. Ruptured pathology and female sex were excluded from analysis. Patient characteristics, operative details, prostate measurements, and outcomes were abstracted from the electronic medical record. Urinary retention was defined as any requirement of straight catheterization, urinary catheter replacement, or discharge with urinary catheter. Chi square tests and logistic regression were used to determine predictors associated with POUR and increased hospital length of stay.
Among 138 patients who underwent EVAR, eight (5.8%) were excluded due to ruptured pathology. Of the cohort, 113 (86.9%) were male with mean age of 73 years. Excluding female patients, 63 (55.8%) male patients underwent general anesthesia and 50 (44.3%) underwent MAC. Male patients under general anesthesia were more likely to have intra-operative urinary catheter placement when compared to MAC (82.5% vs. 36%, respectively; P < 0.001). POUR was identified in 17 patients (13.1%) of the entire study population with 15 events (88.2%) occurring in males. Excluding patients who were admitted to the ICU, twenty-two (19.5%) male patients stayed past postoperative day (POD) one, of which those who developed POUR were more likely to experience compared to those without POUR (45.6% vs. 9.7%, respectively; P = 0.001). On multivariable analysis, male patients who received MAC had a lower risk of developing POUR (OR 0.09, 95% CI 0.02-0.50). POUR was not associated with elective urinary catheter placement nor with pre-existing conditions such as diabetes, urinary retention, benign prostatic hypertrophy (BPH), or use of BPH medications. Additionally, neither prostate size nor volume was associated with developing POUR among male patients.
MAC plus local anesthesia is associated with decreased rates of POUR after elective EVAR in male patients. ERAS pathways during elective EVAR interventions should implement MAC plus local anesthesia as an acceptable anesthetic option, where appropriate, in order to reduce urinary retention rates and subsequently decrease hospital length of stay in this patient cohort.
手术后快速康复 (ERAS) 方案为大容量手术的术后护理提供了一种简化的方法。血管内主动脉修复 (EVAR) 已成为治疗腹主动脉瘤的标准方法,因此有必要实施早期康复计划。术后尿潴留 (POUR) 仍然是一个问题,导致住院时间延长和患者不适。我们旨在证明监测麻醉护理 (MAC) 加局部麻醉作为减少 EVAR 后尿潴留的一种方法的效用。
对 2017 年 1 月至 2020 年 3 月期间在全麻或 MAC 麻醉下接受标准择期 EVAR 的所有患者进行单中心回顾性研究。所有接受 MAC 的患者均在血管入路部位使用局部麻醉。排除破裂性病变和女性患者进行分析。从电子病历中提取患者特征、手术细节、前列腺测量值和结果。尿潴留定义为任何需要直接导尿、更换导尿管或带导尿管出院的情况。使用卡方检验和逻辑回归来确定与 POUR 和住院时间延长相关的预测因素。
在接受 EVAR 的 138 名患者中,有 8 名(5.8%)因破裂性病变而被排除。在该队列中,113 名(86.9%)为男性,平均年龄为 73 岁。排除女性患者后,63 名(55.8%)男性患者接受全身麻醉,50 名(44.3%)接受 MAC。与 MAC 相比,接受全身麻醉的男性患者术中更有可能放置导尿管(分别为 82.5%和 36%;P<0.001)。整个研究人群中有 17 名(13.1%)患者发生 POUR,其中 15 名(88.2%)发生在男性。排除入住 ICU 的患者后,22 名(19.5%)男性患者在术后第 1 天(POD1)后仍住院,其中发生 POUR 的患者比未发生 POUR 的患者更有可能经历(分别为 45.6%和 9.7%;P=0.001)。多变量分析显示,接受 MAC 的男性患者发生 POUR 的风险较低(OR 0.09,95%CI 0.02-0.50)。POUR 与选择性导尿放置或糖尿病、尿潴留、良性前列腺增生 (BPH) 或使用 BPH 药物等预先存在的疾病无关。此外,在男性患者中,前列腺大小或体积均与发生 POUR 无关。
MAC 加局部麻醉与男性患者选择性 EVAR 后 POUR 发生率降低相关。在择期 EVAR 干预期间,ERAS 途径应将 MAC 加局部麻醉作为一种可接受的麻醉选择,以降低尿潴留发生率,并随后降低该患者队列的住院时间。