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在颈椎固定的成年患者中使用可视探条与可视喉镜进行气管插管的比较:一项随机对照试验的荟萃分析。

Comparison of video-stylet and video-laryngoscope for endotracheal intubation in adults with cervical neck immobilisation: A meta-analysis of randomised controlled trials.

作者信息

Hung Kuo-Chuan, Chang Ying-Jen, Chen I-Wen, Lin Chien-Ming, Liao Shu-Wei, Chin Jo-Chi, Chen Jen-Yin, Yew Ming, Sun Cheuk-Kwan

机构信息

Department of Anaesthesiology, Chi Mei Medical Centre, Tainan City, Taiwan.

Department of Anaesthesiology, Park One International Hospital, Kaohsiung, Taiwan.

出版信息

Anaesth Crit Care Pain Med. 2021 Dec;40(6):100965. doi: 10.1016/j.accpm.2021.100965. Epub 2021 Oct 21.

Abstract

BACKGROUND

The efficacy of video-stylet versus video-laryngoscope for tracheal intubation in patients with cervical spine immobilisation, which is known to impede the intubation process, remains unclear.

METHODS

We searched electronic databases including EMBASE, MEDLINE, Google Scholar, and Cochrane Library for randomised controlled trials comparing video-stylets with video-laryngoscopes in human subjects with cervical spine immobilisation from inception to the 25 of January 2021. The primary outcome was the rate of successful first-attempt intubation, while secondary outcomes included overall intubation success rate, time for successful intubation, and risk of tissue damage.

RESULTS

Five trials (709 patients) published between 2009 and 2020 met the inclusion criteria. There were four types of video-stylets and three types of video-laryngoscopes examined. Hard cervical collar was applied in four studies, while manual inline stabilisation was used in one study for cervical immobilisation. There was no difference in successful first-attempt intubation rate between the video-stylet and the video-laryngoscope groups [risk ratio (RR) = 0.96, 95% CI: 0.90-1.03, p = 0.3; I = 47%] (5 trials, 709 patients). The overall success rate (RR = 0.98, 95% CI: 0.96-1.0, p = 0.05; I = 0%), intubation time [mean difference (MD) = 5.24, 95% CI: -8.95 to 19.43, p = 0.47; I = 92%], and risk of tissue damage (RR = 0.87, 95% CI: 0.26-2.85, p = 0.81; I = 39%) were also comparable between the two groups.

CONCLUSIONS

This study validates the efficacy of both video-stylets and video-laryngoscopes for tracheal intubation in the situation of cervical spine immobilisation. Further large-scale trials are warranted to support our findings in this clinical setting.

摘要

背景

在已知会妨碍插管过程的颈椎固定患者中,视频管芯喉镜与视频喉镜用于气管插管的疗效仍不明确。

方法

我们检索了电子数据库,包括EMBASE、MEDLINE、谷歌学术和Cochrane图书馆,以查找从数据库建立至2021年1月25日期间,比较视频管芯喉镜与视频喉镜在颈椎固定的人类受试者中应用效果的随机对照试验。主要结局是首次尝试插管成功率,次要结局包括总体插管成功率、成功插管时间和组织损伤风险。

结果

2009年至2020年发表的5项试验(709例患者)符合纳入标准。研究了4种类型的视频管芯喉镜和3种类型的视频喉镜。4项研究应用了硬式颈托,1项研究采用手动轴向固定来进行颈椎固定。视频管芯喉镜组与视频喉镜组的首次尝试插管成功率无差异[风险比(RR)=0.96,95%置信区间:0.90-1.03,p=0.3;I²=47%](5项试验,709例患者)。两组的总体成功率(RR=0.98,95%置信区间:0.96-1.0,p=0.05;I²=0%)、插管时间[平均差(MD)=5.24,95%置信区间:-8.95至19.43,p=0.47;I²=92%]和组织损伤风险(RR=0.87,95%置信区间:0.26-2.85,p=0.81;I²=39%)也相当。

结论

本研究证实了视频管芯喉镜和视频喉镜在颈椎固定情况下用于气管插管的疗效。需要进一步开展大规模试验以支持我们在这一临床环境中的研究结果。

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