Zhu Jianfei, Chen Jiaolei, Zhang Yunhui, Ji Jianwei
Jianfei Zhu, Attending Physician. Department of Neonatology, Yiwu Central Hospital, Yiwu, 322000, China.
Jiaolei Chen, Attending Physician. Department of Neonatology, Yiwu Central Hospital, Yiwu, 322000, China.
Pak J Med Sci. 2021;37(6):1652-1656. doi: 10.12669/pjms.37.6-WIT.4863.
This article is based on deep learning algorithms and uses MRI to study the development of congenital heart septal defects in neonatal brain tissue.
From January 2018 to December 2019, 150 cases of congenital cardiac paper septal defect were retrospectively analyzed on 50 cases of normal newborns and neonates. The four index parametersbrain MR imaging, lateral ventricle pre-angle measurement index (F/F'), body index (D/ D'), caudal nucleus index (C/C') were analyzed. The independent sample t test is performed to compare the difference parameters between groups.
F congenital heart disease group and control group/F 'values were 0.301 ± 0.035 and 0.296 ± 0.031; Evans index was 0.239 ± 0.052 and 0.233 ± 0.025; 2 sets of D/D' values were 0.261 ± 0.039 and 0.234 ± 0.032; C/C 'value was 0.138 ± 0.018 and 0.124 ± 0.015 respectively. The congenital heart disease group D/D ', and the value of C/C' obtained under the ROC curve area value, respectively 0.698 and 0.750, Youden index corresponding to the maximum D/D ', and the value of C/C' values were 0.28 and 0.12.
Lateral ventricle D/D 'and C/C' is more sensitive indicator which can be evaluated with the difference between the volume of congenital heart septal defects in newborn normal neonatal brain; when the D/D 'value> 0.28, C/C' value> 0.12. For the diagnosis and evaluation of congenital heart septal defect neonatal brain volume abnormalities have a certain reference value.
本文基于深度学习算法,利用磁共振成像(MRI)研究新生儿脑组织中先天性心脏间隔缺损的发展情况。
回顾性分析2018年1月至2019年12月期间150例先天性心脏纸隔缺损患儿以及50例正常新生儿和婴儿。分析四个指标参数:脑磁共振成像、侧脑室前角测量指数(F/F')、体指数(D/D')、尾状核指数(C/C')。采用独立样本t检验比较组间差异参数。
先天性心脏病组与对照组的F/F'值分别为0.301±0.035和0.296±0.031;埃文斯指数分别为0.239±0.052和0.233±0.025;两组D/D'值分别为0.261±0.039和0.234±0.032;C/C'值分别为0.138±0.018和0.124±0.015。先天性心脏病组的D/D'以及C/C'值在ROC曲线下面积值分别为0.698和0.750,对应最大D/D'和C/C'值的约登指数分别为0.28和0.12。
侧脑室D/D'和C/C'是更敏感的指标,可用于评估新生儿正常脑内先天性心脏间隔缺损体积的差异;当D/D'值>0.28,C/C'值>0.12时。对先天性心脏间隔缺损新生儿脑体积异常的诊断和评估具有一定参考价值。