Wu Peng, Xiang Wenjing, Yin Chengke, Li Shu
Artificial Organ Technology Laboratory, School of Mechanical and Electric Engineering, Soochow University, Suzhou, China.
Institute for Medical Device Control, National Institutes for Food and Drug Control, Beijing, China.
Front Physiol. 2021 Oct 14;12:766867. doi: 10.3389/fphys.2021.766867. eCollection 2021.
In recent years, blood pumps have become the bridge to heart transplantation for patients with heart failure. Portability and wearability of blood pumps should be considered to ensure patient satisfaction in everyday life. To date, the focus has been on the development of portable and wearable peripheral components, little attention has been paid to the portable and wearable performance of the blood pump itself. This study reported a novel design of a wearable and portable extracorporeal centrifugal blood pump. Based on an in-house centrifugal maglev blood pump, the wearable and portable blood pump was designed with parallel inlet and outlet pipes to improve the wearable performance. A ring cavity was set at the inlet to convert the circumferential velocity of the inlet pipe to an axial velocity. The hydraulic and hemolytic performance of the baseline and portable blood pumps were analyzed and compared. Compared with the baseline pump, the hydrodynamic and hemolytic performance of the portable pump has been maintained without serious degradation. The results of this study will improve the life quality of patients with heart failure, and enhance the clinical benefits of artificial heart.
近年来，血泵已成为心力衰竭患者心脏移植的桥梁。应考虑血泵的便携性和可穿戴性，以确保患者在日常生活中的满意度。迄今为止，重点一直放在便携式和可穿戴外周组件的开发上，而对血泵本身的便携式和可穿戴性能关注甚少。本研究报告了一种可穿戴和便携式体外离心血泵的新颖设计。基于内部离心磁悬浮血泵，该可穿戴和便携式血泵采用平行进、出口管道进行设计，以提高可穿戴性能。在入口处设置了一个环形腔，将入口管道的圆周速度转换为轴向速度。对基线血泵和便携式血泵的水力和溶血性能进行了分析和比较。与基线泵相比，便携式泵的流体动力学和溶血性能得以保持，没有严重下降。本研究结果将改善心力衰竭患者的生活质量，并提高人工心脏的临床效益。
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