肿瘤免疫学中的成像技术。
Imaging in Tumor Immunology.
作者信息
Kim Euishin Edmund, Youn Hyewon, Kang Keon Wook
机构信息
Department of Radiological Sciences, UCI Medical Center, Orange County, CA USA.
Department of Nuclear Medicine, Seoul National University Hospital, Seoul, South Korea.
出版信息
Nucl Med Mol Imaging. 2021 Oct;55(5):225-236. doi: 10.1007/s13139-021-00706-6. Epub 2021 Jul 27.
Recent advances in immune modulation have made impressive progress in cancer immunotherapy. Because dynamic nature of the immune response often makes it difficult to evaluate therapeutic outcomes, innovative imaging technologies have been developed to enable non-invasive visualization of immune cells and tumors in their microenvironment. This review summarizes the current tumor immunology and describes new innovative imaging methods with great potential to obtain non-invasive real-time insights into the complex functions of the immune system and into the management of cancer immunotherapy.
免疫调节方面的最新进展在癌症免疫治疗中取得了令人瞩目的成果。由于免疫反应的动态特性常常使得评估治疗效果变得困难，因此已经开发出创新的成像技术，以实现对免疫细胞及其微环境中肿瘤的非侵入性可视化。本综述总结了当前的肿瘤免疫学，并描述了具有巨大潜力的新型创新成像方法，这些方法能够对免疫系统的复杂功能以及癌症免疫治疗的管理进行非侵入性实时洞察。
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