急性淋巴细胞白血病化疗后出现的爆发性肢端雀斑样痣：病例系列
Eruptive acral lentiginosis following chemotherapy for acute lymphoblastic leukemia: A case series.
作者信息
O'Connor Cathal, Ryan Clodagh, Murphy Lesley-Ann
机构信息
Department of Dermatology South Infirmary Victoria University Hospital Cork Ireland.
Department of Paediatrics and Child Health University College Cork Cork Ireland.
出版信息
Clin Case Rep. 2021 Oct 28;9(10):e05015. doi: 10.1002/ccr3.5015. eCollection 2021 Oct.
Lentigines are brown macules which develop due to increased proliferation of melanocytes at the dermo-epidermal junction. We report three cases of acral lentiginosis in children following chemotherapy for acute lymphoblastic leukaemia (ALL) which have persisted following cessation of chemotherapy, despite avid photoprotection. Generalised eruptive naevi with subsequent development of dysplastic naevi and melanoma in situ have been reported following chemotherapy, highlighting the importance of continued clinical observation.
雀斑样痣是由于真皮-表皮交界处黑素细胞增殖增加而形成的褐色斑疹。我们报告了3例急性淋巴细胞白血病（ALL）化疗后的儿童肢端雀斑样痣病例，尽管采取了积极的光防护措施，但化疗停止后这些雀斑样痣仍持续存在。化疗后曾有全身性发疹性痣随后发展为发育异常痣和原位黑素瘤的报道，这凸显了持续临床观察的重要性。
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