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胃肠道癌症与肝硬化:对治疗及预后的影响

Gastrointestinal Cancers and Liver Cirrhosis: Implications on Treatments and Prognosis.

作者信息

Xiang Ze, Li Yiqi, Zhu Chaojie, Hong Tu, He Xianglin, Zhu Hua, Jiang Danbin

机构信息

Department of Gastroenterology, Yancheng Third People's Hospital, Yancheng, China.

School of Medicine, Zhejiang University, Hangzhou, China.

出版信息

Front Oncol. 2021 Oct 21;11:766069. doi: 10.3389/fonc.2021.766069. eCollection 2021.

Abstract

Liver cirrhosis tends to increase the risk in the management of gastrointestinal tumors. Patients with gastrointestinal cancers and liver cirrhosis often have serious postoperative complications and poor prognosis after surgery. Multiple studies have shown that the stage of gastrointestinal cancers and the grade of cirrhosis can influence surgical options and postoperative complications. The higher the stage of cancer and the poorer the degree of cirrhosis, the less the surgical options and the higher the risk of postoperative complications. Therefore, in the treatment of patients with gastrointestinal cancer and liver cirrhosis, clinicians should comprehensively consider the cancer stage, cirrhosis grade, and possible postoperative complications. This review summarizes the treatment methods of patients with different gastrointestinal cancer complicated with liver cirrhosis.

摘要

肝硬化往往会增加胃肠道肿瘤治疗的风险。患有胃肠道癌症和肝硬化的患者术后常出现严重并发症,且术后预后较差。多项研究表明,胃肠道癌症的分期和肝硬化的分级会影响手术选择和术后并发症。癌症分期越高、肝硬化程度越差,手术选择越少,术后并发症风险越高。因此,在治疗胃肠道癌症合并肝硬化的患者时,临床医生应综合考虑癌症分期、肝硬化分级以及可能出现的术后并发症。本综述总结了不同胃肠道癌症合并肝硬化患者的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6b7/8567751/af4f02c016d4/fonc-11-766069-g001.jpg

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