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在高负担社区中测试前列腺癌教育干预措施。

Testing a Prostate Cancer Educational Intervention in High-Burden Neighborhoods.

机构信息

Department of Medical Oncology, Thomas Jefferson University, Philadelphia, PA, USA.

Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.

出版信息

J Racial Ethn Health Disparities. 2022 Dec;9(6):2477-2484. doi: 10.1007/s40615-021-01183-5. Epub 2021 Nov 8.

Abstract

To better capitalize on our enhanced understanding of prostate cancer (PCa) risk factors, it is important to better understand how knowledge and attitudes contribute to ethnic disparities in PCa outcomes. The goal of this study was to test the impact of a targeted PCa educational intervention vs. a healthy lifestyle educational control intervention on levels of knowledge, concern, and intention to screen for PCa.We recruited 239 men from neighborhoods with the highest PCa burden in Philadelphia. We assigned 118 men from two of the neighborhoods to the control group 121 men from 2 other neighborhoods to the intervention group. Repeated outcome assessment measures were obtained by administering the survey at baseline, post-session, 1 month post-session, and 4 months post-session.We conducted descriptive statistics to characterize the study sample and linear mixed effect regression models to analyze the intervention's effect on the outcomes. At baseline, we observed no differences in the outcomes between the PCa-targeted intervention and healthy lifestyle control groups.We found that knowledge of PCa and intention to screen increased significantly over time for both the control and intervention groups (p ≤ 0.01 at the 4-month follow-up). In contrast, change in the level of PCa concern was only significant for the intervention group immediately post-session and at 1-month follow-up (p = 0.04 and p = 0.01, respectively).This study showed that gathering at-risk men for discussions about PCa or other health concerns may increase their PCa knowledge and intention to talk to a doctor about PCa screening.

摘要

为了更好地利用我们对前列腺癌(PCa)危险因素的深入了解,重要的是要更好地了解知识和态度如何导致 PCa 结果的种族差异。本研究的目的是测试针对前列腺癌的教育干预与健康生活方式教育对照干预对知识、关注和进行前列腺癌筛查的意愿水平的影响。

我们从费城 PCa 负担最高的社区招募了 239 名男性。我们将来自两个社区的 118 名男性分配到对照组,将来自另外两个社区的 121 名男性分配到干预组。通过在基线、会议后、会议后 1 个月和会议后 4 个月进行调查来获得重复的结果评估测量。

我们进行了描述性统计分析,以描述研究样本,并进行线性混合效应回归模型分析干预对结果的影响。在基线时,我们观察到针对 PCa 的干预与健康生活方式对照组之间在结果上没有差异。

我们发现,无论是对照组还是干预组,对 PCa 的了解和进行筛查的意愿都随着时间的推移显著增加(在 4 个月随访时均为 p≤0.01)。相比之下,PCa 关注程度的变化仅在干预组在会议后立即和 1 个月随访时具有统计学意义(分别为 p=0.04 和 p=0.01)。

本研究表明,召集高危男性讨论 PCa 或其他健康问题可能会增加他们对 PCa 的了解,并增加他们与医生谈论 PCa 筛查的意愿。

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