胰岛素百年史：胰岛素为何如此昂贵，以及有哪些控制其成本的措施？
100 years of Insulin: Why is Insulin So Expensive and What Can be Done to Control Its Cost?
机构信息
Division of Metabolism, Endocrinology & Diabetes, Department of Internal Medicine, University of Michigan Medical School, 1000 Wall Street, Brehm Tower, Room 6108, Ann Arbor, MI 48105, USA; Department of Epidemiology, University of Michigan School of Public Health, 1000 Wall Street, Brehm Tower, Room 6115, Ann Arbor, MI 48105, USA.
Division of Metabolism, Endocrinology & Diabetes, Department of Internal Medicine, University of Michigan Medical School, 1000 Wall Street, Brehm Tower, Room 6108, Ann Arbor, MI 48105, USA.
出版信息
Endocrinol Metab Clin North Am. 2021 Sep;50(3S):e21-e34. doi: 10.1016/j.ecl.2021.09.001. Epub 2021 Oct 14.
The discovery of insulin 100 years ago and subsequent improvements in insulin formulations and delivery devices have changed the lives of people with diabetes. Unfortunately, the average price of insulin in the United States has nearly tripled over the past decade, and the high cost of insulin has become a barrier to diabetes treatment. On the 100th anniversary of insulin's discovery, this life-saving treatment is financially out of reach for as many as one-third of people with diabetes. The challenge now is to ensure that insulin is available for all people with diabetes who need it. We explore reasons for the high cost of insulin and recommend some clinical and policy interventions to improve insulin access and affordability.
胰岛素发现 100 年来，胰岛素制剂和给药装置的不断改进改变了糖尿病患者的生活。遗憾的是，过去十年间，美国胰岛素的平均价格几乎翻了三倍，而胰岛素的高昂费用已成为糖尿病治疗的障碍。在胰岛素发现 100 周年之际，多达三分之一的糖尿病患者因经济原因无法获得这种救命治疗。当前的挑战是确保所有有需要的糖尿病患者都能获得胰岛素。我们探讨了胰岛素价格居高不下的原因，并提出了一些改善胰岛素可及性和可负担性的临床和政策干预措施。
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