Amin Faiza, Rahman Sehrish, Khurshid Zohaib, Zafar Muhammad Sohail, Sefat Farshid, Kumar Naresh
Science of Dental Materials Department, Dow Dental College, Dow University of Health Sciences, Karachi 74200, Pakistan.
Science of Dental Materials Department, Dr. Ishrat Ul Ebad Khan Institute of Oral Health Sciences, Dow University of Health Sciences, Karachi 74200, Pakistan.
Materials (Basel). 2021 Oct 21;14(21):6260. doi: 10.3390/ma14216260.
Overall perspective of nanotechnology and reinforcement of dental biomaterials by nanoparticles has been reported in the literature. However, the literature regarding the reinforcement of dental biomaterials after incorporating various nanostructures is sparse. The present review addresses current developments of glass ionomer cements (GICs) after incorporating various metallic, polymeric, inorganic and carbon-based nanostructures. In addition, types, applications, and implications of various nanostructures incorporated in GICs are discussed. Most of the attempts by researchers are based on the laboratory-based studies; hence, it warrants long-term clinical trials to aid the development of suitable materials for the load bearing posterior dentition. Nevertheless, a few meaningful conclusions are drawn from this substantial piece of work; they are as follows: (1) most of the nanostructures are likely to enhance the mechanical strength of GICs; (2) certain nanostructures improve the antibacterial activity of GICs against the cariogenic bacteria; (3) clinical translation of these promising outcomes are completely missing, and (4) the nanostructured modified GICs could perform better than their conventional counterparts in the load bearing posterior dentition.
纳米技术的总体情况以及纳米颗粒对牙科生物材料的增强作用已在文献中有所报道。然而,关于在纳入各种纳米结构后牙科生物材料增强作用的文献却很稀少。本综述阐述了在纳入各种金属、聚合物、无机和碳基纳米结构后玻璃离子水门汀(GICs)的当前发展情况。此外,还讨论了纳入GICs中的各种纳米结构的类型、应用及影响。研究人员的大多数尝试都基于实验室研究;因此,需要进行长期临床试验,以助力开发适用于后牙承重的材料。尽管如此,从这项大量的工作中得出了一些有意义的结论,如下所示:(1)大多数纳米结构可能会增强GICs的机械强度;(2)某些纳米结构可提高GICs对致龋菌的抗菌活性;(3)这些有前景的结果完全缺乏临床转化;(4)纳米结构改性的GICs在承重后牙中可能比传统同类产品表现更好。