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2011 年至 2018 年期间,高血压成年人中抗高血压药物使用和血压控制的种族和民族差异的国家趋势。

National Trends in Racial and Ethnic Disparities in Antihypertensive Medication Use and Blood Pressure Control Among Adults With Hypertension, 2011-2018.

机构信息

Center for Outcomes Research and Evaluation, Yale New Haven Hospital, New Haven, CT (Y. Lu, Y. Liu, L.S.D., D.M., C.C., S.M., E.S.S., O.O., H.M.K.).

Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT (Y. Lu, Y. Liu, L.S.D., D.M., C.C., S.M., E.S.S., O.O., J.H., H.M.K.).

出版信息

Hypertension. 2022 Jan;79(1):207-217. doi: 10.1161/HYPERTENSIONAHA.121.18381. Epub 2021 Nov 15.

DOI:10.1161/HYPERTENSIONAHA.121.18381
PMID:34775785
Abstract

Poor hypertension awareness and underuse of guideline-recommended medications are critical factors contributing to poor hypertension control. Using data from 8095 hypertensive people aged ≥18 years from the National Health and Nutrition Examination Survey (2011-2018), we examined recent trends in racial and ethnic differences in awareness and antihypertensive medication use, and their association with racial and ethnic differences in hypertension control. Between 2011 and 2018, age-adjusted hypertension awareness declined for Black, Hispanic, and White individuals, but the 3 outcomes increased or did not change for Asian individuals. Compared with White individuals, Black individuals had a similar awareness (odds ratio, 1.20 [0.96-1.45]) and overall treatment rates (1.04 [0.84-1.25]), and received more intensive antihypertensive medication if treated (1.41 [1.27-1.56]), but had a lower control rate (0.72 [0.61-0.83]). Asian and Hispanic individuals had significantly lower awareness rates (0.69 [0.52-0.85] and 0.74 [0.59-0.89]), overall treatment rates (0.72 [0.57-0.88] and 0.69 [0.55-0.82]), received less intensive medication if treated (0.60 [0.50-0.72] and 0.86 [0.75-0.96]), and had lower control rates (0.66 [0.54-0.79] and 0.69 [0.57-0.81]). The racial and ethnic differences in awareness, treatment, and control persisted over the study period and were consistent across age, sex, and income strata. Lower awareness and treatment were significantly associated with lower control in Asian and Hispanic individuals (<0.01 for all) but not in Black individuals. These findings highlight the need for interventions to improve awareness and treatment among Asian and Hispanic individuals, and more investigation into the downstream factors that may contribute to the poor hypertension control among Black individuals.

摘要

高血压知晓率低且指南推荐药物使用率低是导致高血压控制不佳的关键因素。我们利用美国国家健康和营养调查(2011-2018 年)中 8095 名年龄≥18 岁的高血压患者的数据,研究了近年来不同种族和族裔在知晓率和降压药物使用方面的差异趋势,以及这些差异与高血压控制情况之间的关系。在 2011 年至 2018 年间,黑种人、西班牙裔和白人的高血压知晓率呈调整年龄后的下降趋势,但亚洲人的这 3 项指标有所增加或保持不变。与白人相比,黑种人知晓率相近(比值比,1.20 [0.96-1.45]),总体治疗率也相近(1.04 [0.84-1.25]),如果接受治疗,接受更强化降压药物治疗的比例更高(1.41 [1.27-1.56]),但控制率更低(0.72 [0.61-0.83])。亚洲人和西班牙裔人的知晓率显著较低(0.69 [0.52-0.85]和 0.74 [0.59-0.89]),总体治疗率也较低(0.72 [0.57-0.88]和 0.69 [0.55-0.82]),如果接受治疗,接受更强化药物治疗的比例较低(0.60 [0.50-0.72]和 0.86 [0.75-0.96]),控制率也较低(0.66 [0.54-0.79]和 0.69 [0.57-0.81])。在研究期间,知晓率、治疗率和控制率方面的种族和族裔差异持续存在,且在年龄、性别和收入阶层上具有一致性。知晓率和治疗率较低与亚洲人和西班牙裔人的控制率较低显著相关(所有 P<0.01),但与黑种人无关。这些发现强调需要采取干预措施来提高亚洲人和西班牙裔人的知晓率和治疗率,并进一步研究可能导致黑种人高血压控制不佳的下游因素。

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