Obstetrics and Gynecology, Pennsylvania Hospital, Philadelphia, Pennsylvania, USA.
Pelvic Anatomy Group - Imaging, Society of Gynecologic Surgeons, East Dundee, Illinois, USA.
Neurourol Urodyn. 2022 Jan;41(1):340-347. doi: 10.1002/nau.24826. Epub 2021 Nov 22.
To evaluate differences in the curvature of the urethral-vaginal interface in women with and without stress urinary incontinence (SUI) using geometric morphometric analysis techniques.
We conducted a pilot case-control study using magnetic resonance imaging (MRI) scans of 18 women with and without SUI. The urethral-vaginal interface at the level of the mid-urethra was fitted with a second-order polynomial regression. The chord length and chord-to-vertex length of the resulting parabolic curve were used to calculate the arc length and radius of a circular arc fitted to the interface curvature. Demographic characteristics and Pelvic Organ Prolapse Quantification (POP-Q) parameters were collected. Subjects were stratified by those with and without SUI, as well as by those with and without anterior wall prolapse beyond 2 cm proximal to the hymen (Aa > -2 cm).
The radius of the urethral-vaginal interface curvature was not found to be different between subjects with and without SUI (8.8 vs. 9.2 mm, p = 0.53); however, this value was smaller in subjects with Aa > -2 (8.4 vs. 11.9 mm, p = 0.03). The chord length, chord-to-vertex length, and arc length comprising the urethral-vaginal interface curvature were similar between subjects with and without SUI, and between subjects with and without Aa > -2 cm (p > 0.05 for all).
In this pilot study population, the radius of the urethral-vaginal interface curvature at the mid-urethra was smaller among women with anterior vaginal wall prolapse beyond 2 cm proximal to the hymen. A difference in the urethral-vaginal interface curvature among women with and without SUI was not found.
使用几何形态测量分析技术评估有和无压力性尿失禁（SUI）女性的尿道阴道交界处曲率的差异。
我们进行了一项试点病例对照研究，使用了 18 名有和无 SUI 女性的磁共振成像（MRI）扫描。在中尿道水平，尿道阴道交界处拟合二阶多项式回归。所得抛物线曲线的弦长和弦顶到顶点长度用于计算拟合界面曲率的圆弧的弧长和半径。收集了人口统计学特征和盆腔器官脱垂定量（POP-Q）参数。根据有无 SUI 以及有无处女膜近端 2cm 以上前壁脱垂（Aa > -2cm）对受试者进行分层。
我们未发现有和无 SUI 的受试者之间尿道阴道交界处曲率的半径存在差异（8.8 与 9.2mm，p=0.53）；然而，Aa > -2cm 的受试者的半径较小（8.4 与 11.9mm，p=0.03）。有和无 SUI 的受试者以及有和无 Aa > -2cm 的受试者之间，尿道阴道交界处曲率的弦长、弦顶到顶点长度和弧长相似（p > 0.05）。
在这项试点研究人群中，处女膜近端 2cm 以上前壁脱垂的女性中，中尿道尿道阴道交界处曲率的半径较小。我们未发现有和无 SUI 的女性之间的尿道阴道交界处曲率存在差异。
