Digestive Disease and Surgery Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH, A-10044195, USA.
Division of General Surgery, MetroHealth System, Cleveland, OH, USA.
Surg Endosc. 2022 Jul;36(7):5416-5423. doi: 10.1007/s00464-021-08877-1. Epub 2021 Nov 22.
Multiple retrospective studies have demonstrated the safety and feasibility of laparoscopic median arcuate ligament division with celiac neurolysis for the definitive management of median arcuate ligament syndrome (MALS). This study queries the clinical equipoise of robotic (RMALR) versus laparoscopic MAL release (LMALR) at a high-volume center.
A retrospective analysis of consecutive 26 RMALR and 24 LMALR between March 2018 and August 2019 by a single surgeon at a quaternary academic institution was completed. Primary endpoint was postoperative decrease in celiac trunk expiratory peak systolic velocities (PSVs) measured by mesenteric duplex ultrasonography. Secondary outcomes included reported improvement in MALS-related clinical symptoms, distribution of first assistant seniority level, and involvement of second assistants in RMALR versus LMALR.
Mean operative times for LMALR and RMALR were 86 and 134 min, respectively (p < 0.0001). There were no open conversions and mean length of hospital stay was 1 day for both cohorts. Both groups provided an equally effective decrease in postoperative peak systolic velocities (PSVs) (LMALR p = 0.0011; RMALR p = 0.0022; LMALR vs. RMALR p = 0.7772). While RMALR had significantly higher reduction of chronic abdominal pain postoperatively, there were no significant differences in other postoperative symptom relief between groups. However, RMALR patients reported significant relief of postprandial abdominal pain (p < 0.0001) and chronic nausea (p = 0.0002). RMALR had significantly more junior first assistants (p = 0.0001) and less frequently required second assistants compared to LMALR (p = 0.0381).
In this study comparing RMALR to LMALR, postoperative chronic abdominal pain relief was significantly less in the former while other outcomes were equivalent. In comparison with LMALR, RMALR cases were associated with more junior first assistants, fewer second assistants, and longer operative times. Both approaches are safe and feasible for well-selected patients in experienced centers.
多项回顾性研究已经证实,腹腔镜下正中弓状韧带切断联合腹腔神经松解术治疗正中弓状韧带综合征(MALS)是安全可行的。本研究在一家高容量中心探讨机器人(RMALR)与腹腔镜 MAL 释放(LMALR)的临床均衡性。
对 2018 年 3 月至 2019 年 8 月期间由同一位外科医生进行的 26 例 RMALR 和 24 例 LMALR 连续病例进行回顾性分析。主要终点是肠系膜双功能超声测量的腹腔干呼气峰收缩速度(PSV)术后下降。次要结果包括报告的 MALS 相关临床症状改善、第一助手高级别分布以及 RMALR 与 LMALR 中第二助手的参与情况。
LMALR 和 RMALR 的平均手术时间分别为 86 分钟和 134 分钟(p<0.0001)。两组均无开放转化,平均住院时间均为 1 天。两组均能有效降低术后 PSV(LMALR p=0.0011;RMALR p=0.0022;LMALR 与 RMALR p=0.7772)。虽然 RMALR 术后慢性腹痛的缓解程度明显更高,但两组间其他术后症状缓解无显著差异。然而,RMALR 患者术后餐后腹痛(p<0.0001)和慢性恶心(p=0.0002)的缓解程度明显更高。与 LMALR 相比,RMALR 的初级第一助手明显更年轻(p=0.0001),且较少需要第二助手(p=0.0381)。
在本研究中,RMALR 与 LMALR 相比,前者术后慢性腹痛缓解程度明显较低,而其他结果则相当。与 LMALR 相比,RMALR 病例与更年轻的初级第一助手、更少的第二助手和更长的手术时间相关。在经验丰富的中心,两种方法对精选患者均安全可行。