Conkbayir Cenk, Oztas Didem Melis, Ugurlucan Murat
Cardiology Department, Near East University, Nicosia, Cyprus.
Bagcilar Training and Research Hospital, Istanbul, Turkey.
Arch Med Sci Atheroscler Dis. 2020 Dec 30;5:e332-e334. doi: 10.5114/amsad.2020.103380. eCollection 2020.
Ischemic heart disease is the leading cause of death worldwide. In this study, we evaluated the risk factors for Turkish Cypriot ischemic heart disease patients.
In this study we examined 7017 patients, retrospectively. 5.9% of the patients had myocardial infarction coronary artery disease (MICAD) and 94.1% of the patients were control patients. The mean age of the study population was 52, and 39.2% were female. The risk factors considered were: age, sex, hypertension (HT), diabetes mellitus (DM), family history of coronary artery disease, smoking, high total cholesterol levels and obesity.
Consistently with the presumed risk factors, there was a significant difference between MICAD and control groups in our study for smoking, HT, DM and obesity. However, our study revealed no significant difference for high total cholesterol levels in contrast to the current literature. Assessing the risk factors among male and female patient groups separately, both men and women have the highest risk prevalence for hypertension. Smoking is the second most common risk factor among males, whereas it is the family history of coronary heart disease in the female group. HT, DM and obesity were found to be significant risk factors for both males and females in our study group, while family history was revealed to be significant only in women.
Modifiable risk factors such as smoking, hypertension, diabetes mellitus and obesity may be controlled by lifestyle changes and medical therapies, and should be approached with caution for preventing cardiac events. Non-modifiable risk factors such as age, gender, family history and ethnicity should be taken into account for disease prediction.
缺血性心脏病是全球主要的死亡原因。在本研究中,我们评估了土族塞人缺血性心脏病患者的风险因素。
在本研究中,我们对7017例患者进行了回顾性研究。5.9%的患者患有心肌梗死型冠状动脉疾病(MICAD),94.1%的患者为对照患者。研究人群的平均年龄为52岁,女性占39.2%。所考虑的风险因素包括:年龄、性别、高血压(HT)、糖尿病(DM)、冠状动脉疾病家族史、吸烟、高总胆固醇水平和肥胖。
与假定的风险因素一致,在我们的研究中,MICAD组和对照组在吸烟、HT、DM和肥胖方面存在显著差异。然而,与当前文献相反,我们的研究显示高总胆固醇水平没有显著差异。分别评估男性和女性患者组中的风险因素,男性和女性患高血压的风险患病率最高。吸烟是男性中第二常见的风险因素,而在女性组中则是冠心病家族史。在我们的研究组中,HT、DM和肥胖被发现是男性和女性的重要风险因素,而家族史仅在女性中显示为重要因素。
吸烟、高血压、糖尿病和肥胖等可改变的风险因素可通过生活方式改变和药物治疗加以控制,在预防心脏事件时应谨慎对待。年龄、性别、家族史和种族等不可改变的风险因素在疾病预测中应予以考虑。