CHNHPbBr 薄膜作为导波层，提高等离子体生物传感器的角度灵敏度。

CHNHPbBr Thin Film Served as Guided-Wave Layer for Enhancing the Angular Sensitivity of Plasmon Biosensor.

机构信息

Advanced Institute of Photonics Technology, School of Information Engineering, Guangdong University of Technology, Guangzhou 510006, China.

Guangdong Provincial Key Laboratory of Information Photonics Technology, Guangdong University of Technology, Guangzhou 510006, China.

出版信息

Biosensors (Basel). 2021 Oct 23;11(11):415. doi: 10.3390/bios11110415.

DOI:10.3390/bios11110415

PMID:34821630

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8615843/

Abstract

CHNHPbBr perovskite thin film is used as a guided-wave layer and coated on the surface of an Au film to form the Au-perovskite hybrid structure. Using the hybrid structure, a perovskite-based guided-wave surface plasmon resonance (GWSPR) biosensor is proposed with high angular sensitivity. First, it is found that the electric field at the sensing interface is improved by the CHNHPbBr perovskite thin film, thereby enhancing the sensitivity. The result demonstrates that the angular sensitivity of the Au-perovskite-based GWSPR biosensor is as high as 278.5°/RIU, which is 110.2% higher than that of a conventional Au-based surface plasmon resonance (SPR) biosensor. Second, the selection of the coupling prism in the configuration of the GWSPR biosensor is also analyzed, and it indicates that a low refractive index (RI) prism can generate greater sensitivity. Therefore, the low-RI BK7 prism is served as the coupling prism for the proposed GWSPR biosensor. Finally, the proposed GWSPR sensing structure can not only be used for liquid sensing, but also for gas sensing, and it has also been demonstrated that the GWSPR gas sensor is 2.8 times more sensitive than the Au-based SPR gas sensor.

摘要

CHNHPbBr 钙钛矿薄膜用作导波层并涂覆在 Au 膜的表面上，形成 Au-钙钛矿混合结构。利用该混合结构，提出了一种基于钙钛矿的导波表面等离子体共振（GWSPR）生物传感器，具有高角度灵敏度。首先，发现 CHNHPbBr 钙钛矿薄膜提高了传感界面处的电场，从而提高了灵敏度。结果表明，基于 Au-钙钛矿的 GWSPR 生物传感器的角度灵敏度高达 278.5°/RIU，比传统的基于 Au 的表面等离子体共振（SPR）生物传感器高 110.2%。其次，还分析了 GWSPR 生物传感器配置中耦合棱镜的选择，表明低折射率（RI）棱镜可以产生更大的灵敏度。因此，低 RI 的 BK7 棱镜被用作所提出的 GWSPR 生物传感器的耦合棱镜。最后，所提出的 GWSPR 传感结构不仅可用于液体传感，还可用于气体传感，并且已经证明 GWSPR 气体传感器比基于 Au 的 SPR 气体传感器灵敏 2.8 倍。