Department of Plastic and Reconstructive Surgery, CHA University Bundang Medical Center, Seongnam-si, Gyeonggi-do, Korea.
Department of Plastic and Reconstructive Surgery, Hanyang University College of Medicine, Seoul, Korea.
Sci Rep. 2021 Nov 30;11(1):23185. doi: 10.1038/s41598-021-02530-6.
Chronic hand ischemia causes cold intolerance, intractable pain, and digital ulceration. If ischemic symptoms persist despite pharmacologic treatments, surgical interventions should be considered. This retrospective study evaluated the long-term results after ulnar and radial reconstruction using an interpositional deep inferior epigastric artery (DIEA) graft combined with periarterial sympathectomy. Patients who underwent this surgery from March 2003 to February 2019 were included. To evaluate variables influencing recurrence after the procedure, patients were divided into the recurred and non-recurred groups and their data were compared. Overall, 62 cases involving 47 patients were analyzed (16 and 46 cases in the recurred and non-recurred groups, respectively). The median DIEA graft length was 8.5 cm. The rates of rheumatic disease and female patients were significantly higher in the recurred than in the non-recurred group, without significant between-group differences in postoperative complication rates. In the multivariate analysis, underlying rheumatic disease and graft length had significant effects on recurrence. In Kaplan-Meier analysis, the 5- and 10-year symptom-free rates were 81.3% and 68.0%, respectively, with lower rates for cases with rheumatic disease. Thus, arterial reconstruction using an interpositional DIEA graft provides long-term sustainable vascular supply in patients with chronic hand ischemia, especially in those without rheumatic disease.
慢性手部缺血会导致怕冷、顽固性疼痛和指端溃疡。如果药物治疗后仍存在缺血症状,应考虑手术干预。本回顾性研究评估了采用带蒂腹壁下深动脉(DIEA)移植物联合动脉周围交感神经切除术进行尺侧和桡侧重建后的长期效果。纳入 2003 年 3 月至 2019 年 2 月期间接受该手术的患者。为了评估手术后复发的影响因素,将患者分为复发组和未复发组,并比较其数据。共有 62 例患者(47 例患者中有 16 例和 46 例患者)纳入分析。DIEA 移植物的中位长度为 8.5cm。复发组中风湿性疾病和女性患者的比例明显高于未复发组,但术后并发症发生率无明显差异。多变量分析显示,基础风湿性疾病和移植物长度对复发有显著影响。在 Kaplan-Meier 分析中,5 年和 10 年无症状生存率分别为 81.3%和 68.0%,风湿性疾病患者的生存率较低。因此,采用带蒂 DIEA 移植物的动脉重建为慢性手部缺血患者提供了长期可持续的血管供应,尤其是对于没有风湿性疾病的患者。