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睡眠障碍、心理功能障碍、疼痛强度以及疼痛对慢性疼痛儿童的干扰之间的关联。

The Associations Between Sleep Disturbance, Psychological Dysfunction, Pain Intensity, and Pain Interference in Children with Chronic Pain.

机构信息

Universitat Rovira i Virgili, Unit for the Study and Treatment of Pain - ALGOS, Research Center for Behavior Assessment (CRAMC), Department of Psychology, Catalonia, Spain.

Institut d'Investigació Sanitària Pere Virgili; Universitat Rovira i Virgili, Catalonia, Spain.

出版信息

Pain Med. 2022 May 30;23(6):1106-1117. doi: 10.1093/pm/pnab333.

Abstract

OBJECTIVES

This study aimed to better understand the associations between both sleep disturbance and psychological dysfunction (i.e., anxiety and depressive symptoms, and anger), and pain intensity and pain interference, in a sample of children with chronic pain.

DESIGN

Cross-sectional design.

METHODS

Three hundred and forty-two children with chronic pain (8-18 years) completed measures assessing pain intensity, pain interference, sleep disturbance, anxiety, depressive symptoms, and anger. Regression analyses examined the direct, interaction (with sex), and mediation effects of sleep quality and psychological dysfunction on pain intensity and interference.

RESULTS

Sleep disturbance was significantly associated with both pain intensity and pain interference. However, measures of psychological dysfunction were associated significantly only with pain interference. Sex did not moderate these associations. The measures of psychological dysfunction mediated the associations between sleep disturbance and pain interference but not those between sleep disturbance and pain intensity.

CONCLUSIONS

The results confirmed significant cross-sectional associations between both sleep disturbance and psychological dysfunction and pain outcomes in children with chronic pain. Future research to test for causal associations is warranted.

摘要

目的

本研究旨在更好地理解睡眠障碍与心理功能障碍(即焦虑和抑郁症状、愤怒)以及疼痛强度和疼痛干扰之间的关联,研究对象为患有慢性疼痛的儿童。

设计

横断面设计。

方法

342 名患有慢性疼痛(8-18 岁)的儿童完成了评估疼痛强度、疼痛干扰、睡眠障碍、焦虑、抑郁症状和愤怒的量表。回归分析检查了睡眠质量和心理功能障碍对疼痛强度和干扰的直接、交互(与性别)和中介效应。

结果

睡眠障碍与疼痛强度和疼痛干扰均显著相关。然而,心理功能障碍的测量仅与疼痛干扰显著相关。性别没有调节这些关联。心理功能障碍的测量指标在睡眠障碍与疼痛干扰之间存在中介作用,但在睡眠障碍与疼痛强度之间没有中介作用。

结论

结果证实了患有慢性疼痛的儿童中,睡眠障碍和心理功能障碍与疼痛结果之间存在显著的横断面关联。需要进行未来的研究来测试因果关系。

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