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波多黎各 2015-2019 年飓风玛丽亚对 HPV、Tdap 和脑膜炎球菌结合疫苗接种率的影响。

Effect of Hurricane Maria on HPV, Tdap, and meningococcal conjugate vaccination rates in Puerto Rico, 2015-2019.

机构信息

Puerto Rico Cancer Control and Population Sciences Division, University of Puerto Rico Comprehensive Cancer Center, San Juan, Puerto Rico.

Department of Health Services Administration, Graduate School of Public Health, University of Puerto Rico Medical Science Campus, San Juan, Puerto Rico.

出版信息

Hum Vaccin Immunother. 2021 Dec 2;17(12):5623-5627. doi: 10.1080/21645515.2021.2004809.

Abstract

In September 2017, Hurricane Maria devastated the Caribbean region, among them the US territory of Puerto Rico (PR). Vaccination distribution and uptake suffered from the impact. This study evaluated the trends in monthly vaccination initiation rates for human papilloma virus (HPV), Tdap and meningococcal conjugate (MenACWY) adolescent vaccines from 2015 to 2019, during which it was possible to observe and analyze the impact of Hurricane Maria on vaccine initiation. Monthly initiation rates were estimated. Age-standardized initiation rate ratio (SRR) and 95% CI were estimated. The analysis included 85,340 adolescents; 52.3% were male, and 47.7% were females. September 2017 showed HPV vaccine initiation had the lower rates of all the studied vaccines, with a rate of 75% after the disaster (from a rate of almost 90% in July 2017). Tdap and MenACWY vaccines rates remained above 90% in the same period. The SRR of HPV vaccine for September and October 2017 showed an estimated reduction of 5% and 8% in vaccine initiation rates, respectively for each month, when 2016 was the reference year ( > .05). The SRR of Tdap and MenACWY vaccines for November 2017 showed significant reductions when 2015 and 2016 were reference years ( < .05). HPV vaccine initiation rate was the most severely affected by the Hurricane Maria. Post-natural disaster protocols should strengthen existing programs for facilitate immunization access.

摘要

2017 年 9 月,飓风玛丽亚重创加勒比地区,其中包括美国的波多黎各(PR)。疫苗的分发和接种受到了影响。本研究评估了 2015 年至 2019 年期间 HPV、Tdap 和脑膜炎球菌结合疫苗(MenACWY)青少年疫苗每月接种起始率的趋势,在此期间可以观察和分析飓风玛丽亚对疫苗接种起始率的影响。估计了每月起始率。估计了标准化起始率比(SRR)和 95%CI。分析包括 85340 名青少年;52.3%为男性,47.7%为女性。2017 年 9 月 HPV 疫苗的接种起始率是所有研究疫苗中最低的,灾后的接种率为 75%(2017 年 7 月接近 90%)。同期 Tdap 和 MenACWY 疫苗的接种率仍保持在 90%以上。2017 年 9 月和 10 月 HPV 疫苗的 SRR 估计分别显示,与 2016 年作为参考年相比,每月的疫苗接种起始率分别下降了 5%和 8%(>0.05)。2017 年 11 月 Tdap 和 MenACWY 疫苗的 SRR 显示,当 2015 年和 2016 年作为参考年时,疫苗接种起始率显著下降(<0.05)。HPV 疫苗接种起始率受飓风玛丽亚的影响最为严重。灾后协议应加强现有的免疫获取方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/224d/8903914/4cee06b982f9/KHVI_A_2004809_F0001_B.jpg

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