Heath Travis, O'Mara Keliana, Krushinski Joseph H, Bush Paul
University of North Carolina Eshelman School of Pharmacy, Chapel Hill, NC, USA.
Duke University Medical Center, Durham, NC, USA.
J Pharm Technol. 2015 Oct;31(5):219-222. doi: 10.1177/8755122515578694. Epub 2015 Mar 25.
In the adult population, a high rate of discrepancies exists between provider-performed and pharmacist-performed medication histories. Limited data exist regarding pharmacist-performed medication histories in hospitalized pediatric patients. Identify the incidence and severity of discrepancies in medication histories performed by practitioners compared with pharmacists in the pediatric population. After institutional review board approval, a retrospective analysis of pediatric patients admitted to inpatient pediatric units in a tertiary hospital was performed. The primary endpoint of the study was the percentage of provider-performed medication histories with any discrepancies compared with the pharmacist-performed medication history. Secondary endpoints included the number and type of discrepancies and the discrepancy's potential risk of patient harm. A total of 101 subjects were included. Nineteen patients (18.8%) had at least one medication discrepancy. Missing medications accounted for the majority of the discrepancies. Advance practice providers performed a small number of the initial medication histories (5%) and had at least one discrepancy for each history performed. The percentages of Grades 1, 2, and 3 discrepancies were 57.2%, 17.1%, and 25.7%, respectively. Medications with the most frequent discrepancies included anticonvulsants, antihistamines, and histamine receptor antagonists. Limitations include the retrospective nature of the study and lower than expected discrepancy rate. In this study, 18.8% of pediatric patients had a discrepancy between medication histories. Missing medications accounted for the largest amount of discrepancies. A large percentage of discrepancies had the potential to cause patient harm.
在成年人群中,医护人员所记录的用药史与药剂师所记录的用药史之间存在较高的差异率。关于住院儿科患者药剂师所记录用药史的数据有限。确定儿科人群中从业者与药剂师所记录用药史的差异发生率和严重程度。在获得机构审查委员会批准后,对一家三级医院儿科住院病房收治的儿科患者进行了回顾性分析。该研究的主要终点是与药剂师所记录用药史相比,医护人员所记录用药史存在任何差异的百分比。次要终点包括差异的数量和类型以及差异对患者造成伤害的潜在风险。总共纳入了101名受试者。19名患者(18.8%)至少存在一处用药差异。漏记药物占差异的大部分。高级执业医护人员记录的初始用药史数量较少(5%),且每次记录至少有一处差异。1级、2级和3级差异的百分比分别为57.2%、17.1%和25.7%。差异最频繁出现的药物包括抗惊厥药、抗组胺药和组胺受体拮抗剂。局限性包括研究的回顾性性质以及低于预期的差异率。在本研究中,18.8%的儿科患者用药史存在差异。漏记药物占差异的最大比例。很大一部分差异有可能对患者造成伤害。