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序贯冠状动脉搭桥术。长期随访。

Sequential coronary bypass grafts. Long-term follow-up.

作者信息

Kieser T M, FitzGibbon G M, Keon W J

出版信息

J Thorac Cardiovasc Surg. 1986 May;91(5):767-72.

PMID:3486326
Abstract

Sequential venous coronary bypass grafts have presented problems, mainly because of commonly reported differences between patency of side-to-side and end-to-side vein-coronary anastomoses. Better to define this, we have studied sequential anastomosis grafts done during a 13 year period. We concentrated specifically on 212 "double" grafts with 100% selective angiographic follow-up early, 90% at 1-year, and 44% at 5 years after operation. Four hundred twenty-four control single grafts were studied similarly. We found that patency rates of side-to-side anastomoses were much better than those of end-to-side anastomoses, whether of sequential or control single grafts. Considering specifically diagonal coronary artery-anterior descending coronary artery sequential grafts, the combined patency of all sequential anastomoses theoretically exceeds that of a comparable number of single grafts at all times of study, but the differences are small. Furthermore, there is definite danger of preserving proximal and perhaps limited bypass runoff at the cost of losing distal and perhaps more important myocardial perfusion. On balance, we believe that single vein grafts are to be preferred over sequential grafts unless shortage of conduit material or local aortic wall conditions dictate otherwise.

摘要

序贯静脉冠状动脉搭桥术存在一些问题,主要原因是普遍报道的侧侧和端端静脉 - 冠状动脉吻合口通畅率存在差异。为了更好地界定这一点,我们研究了在13年期间进行的序贯吻合术搭桥手术。我们特别关注了212例“双”搭桥手术,术后早期选择性血管造影随访率为100%,1年时为90%,5年时为44%。同样对424例对照单支搭桥手术进行了研究。我们发现,无论是序贯搭桥还是对照单支搭桥,侧侧吻合口的通畅率都远高于端端吻合口。具体考虑对角冠状动脉 - 前降支冠状动脉序贯搭桥,在研究的所有时间点,所有序贯吻合口的联合通畅率理论上都超过了相当数量单支搭桥的通畅率,但差异较小。此外,存在明确的风险,即以牺牲远端且可能更重要的心肌灌注为代价,保留近端并可能限制旁路血流。权衡利弊,我们认为除非导管材料短缺或局部主动脉壁情况另有要求,否则单支静脉搭桥优于序贯搭桥。

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