Universitas Pelita Harapan Faculty of Medicine, Department of Pediatrics, Banten, Indonesia
J Clin Res Pediatr Endocrinol. 2022 Mar 3;14(1):96-101. doi: 10.4274/jcrpe.galenos.2021.2021-8-12. Epub 2021 Dec 6.
Recognition of an overestimation of stunted children in Indonesia when using the World Health Organization Child Growth Standards (WHOCGS) led to the creation of the Indonesian Growth Reference Chart (IGRC) in 2005, with further improvement in 2018. This systematic review aimed to determine whether there is a difference in the diagnosis of stunting when using these two charts. This systematic review is registered in the PROSPERO database (CRD42021259934). Literature research was performed on PubMed, Science Direct, Medline, Scielo, Medrxiv, Research Square, SSRN, and Biorxiv to identify studies published from 2018 onwards that examined the comparison of IGRC and WHOCGS in detecting stunting. Three studies were included in this review. Pooled analysis showed that IGRC resulted in a lower prevalence of stunted and severely stunted children [risk ratio (RR): 0.28 (95% confidence intervals (CI): 0.15-0.51), p<0.0001, I=97%]. Comparison between IGRC and WHOGCS for prevalence of normal height children showed that there was no difference, and this finding was not significant [RR: 1.56 (95% CI: 0.92-2.66), p=0.1, I=100%], and the comparison for prevalence of tall children also showed that there was no difference when using IGRC or WHOGCS, and this finding was also insignificant [RR: 2.02 (95% CI: 0.78-5.20), p=0.14, I=98%]. This meta-analysis showed that stunted and severely stunted Indonesian children are over-represented using WHOCGS. The difference between IGRC and WHOCGS has occurred because of the sample population, as IGRC includes children from all 33 provinces in Indonesia, better reflecting the growth of all children in Indonesia.
当使用世界卫生组织儿童生长标准(WHOCGS)时,印度尼西亚发现低估了发育迟缓儿童的比例,因此于 2005 年创建了印度尼西亚生长参考图表(IGRC),并在 2018 年进一步改进。本系统评价旨在确定使用这两种图表时,发育迟缓的诊断是否存在差异。本系统评价已在 PROSPERO 数据库(CRD42021259934)中注册。在 PubMed、Science Direct、Medline、Scielo、Medrxiv、Research Square、SSRN 和 Biorxiv 上进行文献检索,以确定自 2018 年以来发表的研究,这些研究检查了 IGRC 和 WHOCGS 在检测发育迟缓方面的比较。本综述纳入了三项研究。汇总分析显示,IGRC 导致发育迟缓儿童和严重发育迟缓儿童的患病率较低[风险比(RR):0.28(95%置信区间(CI):0.15-0.51),p<0.0001,I=97%]。IGRC 与 WHOGCS 用于正常身高儿童的患病率比较表明,差异无统计学意义[RR:1.56(95%CI:0.92-2.66),p=0.1,I=100%],而用于高个子儿童的患病率比较也表明,使用 IGRC 或 WHOGCS 时差异无统计学意义,且该结果也不显著[RR:2.02(95%CI:0.78-5.20),p=0.14,I=98%]。本荟萃分析表明,使用 WHOCGS 时,印度尼西亚的发育迟缓儿童和严重发育迟缓儿童比例过高。IGRC 和 WHOCGS 之间的差异是由于样本人群不同所致,因为 IGRC 包含了印度尼西亚所有 33 个省的儿童,更好地反映了印度尼西亚所有儿童的生长情况。