传统中医推拿疗法治疗慢性疲劳综合征的效果：系统评价和荟萃分析方案。
The effects of traditional Chinese manual therapy (Tuina) for chronic fatigue syndrome: A protocol for systematic review and meta-analysis.
机构信息
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Research Institute of Tuina, Shanghai Academy of Traditional Chinese Medicine, Shanghai, China.
出版信息
Medicine (Baltimore). 2021 Nov 5;100(44):e27700. doi: 10.1097/MD.0000000000027700.
BACKGROUND
Chronic fatigue syndrome (CFS) is a common disease and characterized by fatigue, exhaustion, heavy limbs, and dizziness. Tuina, as a traditional Chinese manual therapy, is usually used for CFS in China. Several studies have reported that Tuina can improve fatigue exhaustion, and dizziness of patients with CFS. However, the effects of Tuina for CFS still remain controversial. Therefore, the current systematic review and meta-analysis will be conducted to investigate the effects of Tuina in the management of CFS.
METHODS
The comprehensive electronic search of PubMed, Web of Science, Chinese National Knowledge Infrastructure, Wanfang Database, Embase, Cochrane Library, Chinese Science Citation Database, Technology Periodical Database from their inception to October 2021 will be conducted. Randomized controlled trials of Tuina for CFS will be included in the review. Two independent reviewers will complete the study selection, data extraction, and the risk of bias. The meta-analysis will be conducted using the Review Manager Version 5.3 software. The heterogeneity will be assessed using the I2 statistic and Q statistic. The standardized mean difference and 95% confidence intervals will be calculated based on different heterogeneity. The subgroup analysis will be conducted based on the duration of treatment, age, gender, duration of CFS. Quality of evidence will be assessed using the Grades of Recommendation, Assessment, Development and Evaluation.
RESULTS
The current systematic review and meta-analysis will be to investigate the effects of Tuina in the management of CFS.
CONCLUSION
The conclusion of this study will provide the evidence for the treatment of CFS in the future. It is expected that the conclusions drawn from this review will benefit patients, clinical practitioners and policy makers.
背景
慢性疲劳综合征（CFS）是一种常见疾病，其特征为疲劳、乏力、四肢沉重和头晕。推拿作为一种传统的中医手法治疗，在中国常用于 CFS 的治疗。有几项研究报告称，推拿可以改善 CFS 患者的疲劳、乏力和头晕症状。然而，推拿治疗 CFS 的效果仍存在争议。因此，目前将进行系统评价和荟萃分析，以调查推拿在 CFS 管理中的作用。
方法
全面检索 PubMed、Web of Science、中国知网、万方数据库、Embase、Cochrane 图书馆、中国科学引文数据库、维普中文科技期刊数据库，检索时间从建库至 2021 年 10 月。纳入推拿治疗 CFS 的随机对照试验。两名独立的审查员将完成研究选择、数据提取和偏倚风险评估。使用 Review Manager Version 5.3 软件进行荟萃分析。使用 I2 统计量和 Q 统计量评估异质性。基于不同的异质性，计算标准化均数差和 95%置信区间。将根据治疗持续时间、年龄、性别、CFS 持续时间进行亚组分析。使用推荐、评估、制定和评价分级来评估证据质量。
结果
目前的系统评价和荟萃分析旨在调查推拿在 CFS 管理中的作用。
结论
本研究的结论将为未来 CFS 的治疗提供证据。预计从本综述中得出的结论将使患者、临床医生和决策者受益。
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