Endocrinology, Diabetology and Metabolism Department, Université de Lille, CHU de Lille, Lille, France.
Endocrinology, Diabetology and Metabolism Department, Université de Lille, CHU de Lille, Lille, France; Inserm U1190, 59000 Lille, France.
Ann Endocrinol (Paris). 2022 Feb;83(1):59-62. doi: 10.1016/j.ando.2021.11.006. Epub 2021 Dec 3.
The natriuretic peptide family consists of three biologically active peptides: atrial natriuretic peptide (ANP), brain (or B-type) natriuretic peptide (BNP), and C-type natriuretic peptide (CNP). ANP and BNP, secreted by the heart, act as cardiac hormones, whereas CNP is an endothelial peptide. The aim of this manuscript is to review the production, action mechanisms, effects and clinical applications of natriuretic peptides.
心钠肽(ANP)、脑(或 B 型)利钠肽(BNP)和 C 型利钠肽(CNP)。ANP 和 BNP 由心脏分泌,作为心脏激素发挥作用,而 CNP 是一种内皮肽。本文旨在综述利钠肽的产生、作用机制、作用和临床应用。