Al-Naami Bassam, Abu Owida Hamza, Abu Mallouh Mohammed, Al-Naimat Feras, Agha Moh'd, Al-Hinnawi Abdel-Razzak
Department of Biomedical Engineering, The Hashemite University, Zarqa, Jordan.
Department of Medical Engineering, Al-Ahliyya Amman University, Amman, Jordan.
Med Devices (Auckl). 2021 Dec 2;14:423-433. doi: 10.2147/MDER.S339855. eCollection 2021.
The daily life management of patients with Alzheimer's disease (AD) constitutes a significant and rapidly expanding health-care responsibility. In this study, an innovative prototype of a wireless-sensing smart wearable medical device (SWMD) is proposed as a multi-functions solution for Alzheimer patients. The SWMD is aimed to assemble three main biomedical engineering advances: 1) use of a Wi-Fi microcontroller, 2) simultaneous monitoring of a set of vital biomarkers, and 3) cautions of fall down conditions, in addition to GPS location indicator.
The SWMD employs a Wi-Fi controller that is incorporated with electronic circuits to monitor three vital signals (temperature, heart rate, and oxygen saturation), fall down conditions in three directions (X, Y, and Z axis), and GPS location. The SWMD was connected to the Firebase Service (database hosted on the Internet Cloud). The proposed device was tested on 13 normal volunteers. The left side, right side, forward, and backward fall down conditions were assessed. The prototype's functions during daily activity such as rising hand, sitting down or standing up, and walking conditions were also assessed.
The three assembled functions were all successfully incorporated to build the SWDM device as a suggested solution offering real-time alerts during daily activity to AD patients. The Bland-Altman statistical test showed no significant difference (p-value >0.05) between the SWMD biomarkers' acquisition and the reference methods. The gyro/accelerator sensor yielded 93% sensitivity in fall down detection and 95% specificity during daily activities. The GPS yielded correct positioning of the SWDM holder, while the internet cloud allowed saving and managing all vital biomarkers daily.
The SWMD is a possible solution for daily life support for AD patients. It incorporates three functions in one single device, GPS location indicator, monitoring set of biomarkers, and fall down alert, which are all controlled via a Wi-Fi micro controller on-line connected to Internet Cloud. It successfully would allow the management of the daily records as well as the real-time alerts to remote persons.
阿尔茨海默病(AD)患者的日常生活管理是一项重大且迅速扩展的医疗保健职责。在本研究中,提出了一种无线传感智能可穿戴医疗设备(SWMD)的创新原型,作为针对AD患者的多功能解决方案。该SWMD旨在集成三项主要的生物医学工程进展:1)使用Wi-Fi微控制器;2)同时监测一组重要生物标志物;3)除GPS位置指示器外,还能对跌倒情况发出警示。
SWMD采用一个与电子电路集成的Wi-Fi控制器,以监测三项重要信号(体温、心率和血氧饱和度)、三个方向(X、Y和Z轴)的跌倒情况以及GPS位置。SWMD连接到Firebase服务(托管在互联网云端的数据库)。该拟议设备在13名正常志愿者身上进行了测试。评估了向左、向右、向前和向后跌倒的情况。还评估了该原型在诸如抬手、坐下或站起以及行走等日常活动中的功能。
三项集成功能均成功整合到SWDM设备中,该设备作为一种建议的解决方案,可在日常活动中为AD患者提供实时警报。Bland-Altman统计检验表明,SWMD生物标志物采集与参考方法之间无显著差异(p值>0.05)。陀螺仪/加速度计传感器在跌倒检测中的灵敏度为93%,在日常活动中的特异性为95%。GPS能正确定位SWDM持有者,而互联网云端允许每天保存和管理所有重要生物标志物。
SWMD是为AD患者提供日常生活支持的一种可能解决方案。它在单个设备中集成了三项功能,即GPS位置指示器、生物标志物监测组和跌倒警报,所有这些功能均通过在线连接到互联网云端的Wi-Fi微控制器进行控制。它成功实现了日常记录的管理以及向远程人员发出实时警报。