Garriboli Massimo, Solomon Eskinder
Paediatric Urology, Evelina London Children's Hospital, London, UK.
Stem Cells & Regenerative Medicine Section, Developmental Biology & Cancer Programme, UCL Institute of Child Health, London, UK.
Neurourol Urodyn. 2022 Jan;41(1):448-455. doi: 10.1002/nau.24847. Epub 2021 Dec 9.
To describe a technique for on-table urodynamic with ureteric occlusion (OUUO) and present a case series comparing bladder capacity and pressure measurements performed with and without ureteric occlusion in patients with gross vesico-ureteric reflux (grade ≥ IV VUR) to highlight the clinical utility.
We performed OUUO in seven patients who were being considered for surgical management of VUR and/or nephro-ureterectomy. We occluded the refluxing ureters using hysterosalpingogram catheters (HSG, single lumen 5.5 Fr catheter with 1.5 ml balloon), guidewires, and rigid cystoscope. A 6 Fr dual-lumen urodynamic (UD) catheter is then inserted into the bladder to perform OUUO. Bladder capacity and Compliance (C = ∆bladder volume/∆detrusor pressure) are recorded and compared with values obtained at standard UD (without ureteric occlusion).
The age range of the seven patients was 2.0-15.5 years. The etiology for the gross VUR were posterior urethral valve (PUV) and neuropathic. The bladder capacity and compliance finding between UD and OUUO findings were comparable in five patients. However, there was a clinically significant difference in bladder capacity (20%-50% decrease) and compliance (50%-90%) between UD and OUUO findings in two out of seven patients.
In the presence of gross VUR, OUUO allows for a potentially more accurate assessment of bladder capacity and compliance. OUUO should be considered when planning ureteric opening bulking/reimplantation and nephro-ureterectomy.
描述一种输尿管闭塞下的术中尿动力学技术(OUUO),并呈现一组病例,比较重度膀胱输尿管反流(≥IV级VUR)患者在输尿管闭塞和未闭塞情况下的膀胱容量及压力测量结果,以突出其临床应用价值。
我们对7例正在考虑行VUR手术治疗和/或肾输尿管切除术的患者进行了OUUO。我们使用子宫输卵管造影导管(HSG,单腔5.5F导管,带1.5ml球囊)、导丝和硬性膀胱镜闭塞反流的输尿管。然后插入一根6F双腔尿动力学(UD)导管至膀胱以进行OUUO。记录膀胱容量和顺应性(C = ∆膀胱容量/∆逼尿肌压力),并与标准UD(无输尿管闭塞)时获得的值进行比较。
7例患者的年龄范围为2.0至15.5岁。重度VUR的病因是后尿道瓣膜(PUV)和神经病变。5例患者的UD和OUUO检查结果在膀胱容量和顺应性方面相当。然而,7例患者中有2例在UD和OUUO检查结果之间,膀胱容量(降低20%-50%)和顺应性(降低50%-90%)存在临床上的显著差异。
在存在重度VUR的情况下,OUUO可对膀胱容量和顺应性进行更准确的评估。在计划输尿管开口填充/再植术和肾输尿管切除术时应考虑OUUO。