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在一项针对161,269名德国员工的基于人群的研究中酒渣鼻的流行病学情况。

Epidemiology of rosacea in a population-based study of 161,269 German employees.

作者信息

Hilbring Caroline, Augustin Matthias, Kirsten Natalia, Mohr Nicole

机构信息

Institute for Health Services Research in Dermatology and Nursing (IVDP), University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.

出版信息

Int J Dermatol. 2022 May;61(5):570-576. doi: 10.1111/ijd.15989. Epub 2021 Dec 12.

Abstract

BACKGROUND

Rosacea is a common chronic skin condition, but data on its epidemiology and related comorbidities are scarce.

OBJECTIVES

To analyze the prevalence and associated cutaneous comorbidities of rosacea in Germany.

METHODS

Voluntary dermatological full-body examinations were conducted between 2001 and 2016 in more than 500 German companies by experienced dermatologists and documented electronically. Point-prevalence rates were calculated, and associations were tested with chi-squared tests and logistic regression analysis.

RESULTS

A total of 161,269 participants (mean age was 43.2 ± 10.9 years; 55.5% male) were included; 2.1% had rosacea (men: 2.1%, women 2.1%, mean age 50.7 ± 9.3 years). The prevalence of rosacea increased significantly with age (16-29 years: 0.3%; 30-39 years: 0.9%; 40-49 years: 2.0%; 50-59 years: 3.5%; 60-70 years: 5.7%). Furthermore, there was a significant decreasing prevalence from skin type I toward type IV (skin type I: 3.2%; II: 2.2%; III: 1.5%; IV: 0.4%). The most frequent dermatological comorbidities were: telangiectasia (OR = 2.5), folliculitis (OR = 1.8), seborrheic dermatitis (OR = 1.6), acne (OR = 1.6), tinea pedis (OR = 1.4), psoriasis (OR = 1.4), spider veins (OR = 1.1), and hemangioma (OR = 1.1).

CONCLUSIONS

Rosacea is a common skin condition that is most prevalent above the age of 65 years. Rosacea patients have an increased risk for associated comorbidities. Therefore, the diagnostic and therapeutic process for rosacea patients must ensure an integrated, complete dermatological approach in terms of medical care.

摘要

背景

酒渣鼻是一种常见的慢性皮肤疾病,但关于其流行病学及相关合并症的数据匮乏。

目的

分析德国酒渣鼻的患病率及相关皮肤合并症。

方法

2001年至2016年间,经验丰富的皮肤科医生在500多家德国公司开展了自愿性的皮肤科全身检查,并进行电子记录。计算时点患病率,采用卡方检验和逻辑回归分析检验相关性。

结果

共纳入161,269名参与者(平均年龄43.2±10.9岁;男性占55.5%);2.1%患有酒渣鼻(男性:2.1%,女性2.1%,平均年龄50.7±9.3岁)。酒渣鼻患病率随年龄显著增加(16 - 29岁:0.3%;30 - 39岁:0.9%;40 - 49岁:2.0%;50 - 59岁:3.5%;60 - 70岁:5.7%)。此外,从皮肤类型I到IV患病率显著降低(皮肤类型I:3.2%;II:2.2%;III:1.5%;IV:0.4%)。最常见的皮肤科合并症为:毛细血管扩张(OR = 2.5)、毛囊炎(OR = 1.8)、脂溢性皮炎(OR = 1.6)、痤疮(OR = 1.6)、足癣(OR = 1.4)、银屑病(OR = 1.4)、蜘蛛状静脉(OR = 1.1)和血管瘤(OR = 1.1)。

结论

酒渣鼻是一种常见的皮肤疾病,在65岁以上人群中最为普遍。酒渣鼻患者合并其他疾病的风险增加。因此,酒渣鼻患者的诊断和治疗过程必须确保在医疗护理方面采用综合、全面的皮肤科方法。

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