Albert Einstein College of Medicine, Bronx, New York, USA.
Albert Einstein College of Medicine, Bronx, New York, USA; Department of Medicine, Division of Cardiology, Montefiore Health System, Bronx, New York, USA.
Can J Cardiol. 2022 Mar;38(3):398-400. doi: 10.1016/j.cjca.2021.12.001. Epub 2021 Dec 10.
There are no reports of systemic eosinophilic reactions to durable polymer coated drug eluting stents (DP-DES) and a consensus statement indicates that these devices should be considered in nickel allergy. We present a case of in-stent thrombosis, eosinophilia, and rash consistent with allergic myocardial infarction, a presentation of Kounis syndrome, in the context of metal allergy to DP-DES requiring long-term immunosuppression.
目前尚无关于持久聚合物涂层药物洗脱支架(DP-DES)引起全身嗜酸性粒细胞反应的报告,一份共识声明表明,在镍过敏的情况下应考虑使用这些器械。我们报告了 1 例支架内血栓形成、嗜酸性粒细胞增多和皮疹的病例,该病例符合过敏心肌梗死,即 Kounis 综合征的一种表现,其病因是对 DP-DES 的金属过敏,需要长期免疫抑制治疗。