Department of Anatomical, Histological, Forensic, and Orthopedic Sciences, Sapienza University of Rome, Rome, Italy.
Eur Rev Med Pharmacol Sci. 2021 Dec;25(23):7354-7362. doi: 10.26355/eurrev_202112_27429.
The article aims to elaborate the progress made in partial ectogenesis research on sheep as well as human embryos. Since the ban on embryos experimentation after the 14-day window is a major roadblock in terms of partial ectogenesis research, the authors have weighed the possibility that such a ban could be reconsidered. In favor of easing such a restriction, it may be argued that: (a) unlike the Catholic approach, prevalent ethics precepts hold that the embryo's interest ought to be balanced against the interests of the other parties involved; (b) an extension of the 14-day deadline would no longer make ethically untenable practices acceptable; hence, the "slippery slope" argument, although generally worthy, would not conclusively apply to partial ectogenesis; (c) in mainstream embryo research efforts, there is a conflict between the lives of embryos and the health of individuals already born; as for partial ectogenesis, however, such a conflict would be between the lives of embryos and the lives of fetuses which would not survive otherwise. Still, in light of the embryo's status as a human being, the authors conclude that such research practices should only be allowed on supernumerary embryos.
本文旨在阐述羊和人类胚胎部分外生性研究取得的进展。由于在 14 天窗口期之后禁止胚胎实验是部分外生性研究的主要障碍,作者权衡了重新考虑这一禁令的可能性。为了放宽这种限制,可以认为:(a)与天主教的方法不同,普遍的伦理原则认为,胚胎的利益应该与其他相关方的利益相平衡;(b)延长 14 天的最后期限将不再使在伦理上站不住脚的做法变得可以接受;因此,虽然“滑坡”论点通常是有价值的,但它不会对部分外生性研究具有决定性的影响;(c)在主流胚胎研究工作中,胚胎的生命与已经出生的个人的健康之间存在冲突;而对于部分外生性研究,这种冲突将是在胚胎的生命与否则无法存活的胎儿的生命之间。尽管如此,鉴于胚胎作为人类的地位,作者认为这种研究实践应该只允许在多余的胚胎上进行。