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术前颈椎畸形患者行 1-3 个节段前路减压融合术后与无畸形患者具有相似的临床疗效。

Patients With Preoperative Cervical Deformity Experience Similar Clinical Outcomes to Those Without Deformity Following 1-3 Level Anterior Cervical Decompression and Fusion.

机构信息

Rothman Orthopaedic Institute at Thomas Jefferson University.

Philadelphia College of Osteopathic Medicine, Philadelphia, PA.

出版信息

Clin Spine Surg. 2022 Jun 1;35(5):E466-E472. doi: 10.1097/BSD.0000000000001291. Epub 2021 Dec 20.

Abstract

STUDY DESIGN

Retrospective cohort study.

OBJECTIVE

The aim was to compare the outcomes of patients with incompletely corrected cervical deformity against those without deformity following short-segment anterior cervical decompression and fusion for clinically significant radiculopathy or myelopathy.

SUMMARY OF BACKGROUND DATA

Cervical deformity has increasingly been recognized as a driver of disability and has been linked to worse patient-reported outcomes measures (PROMs) after surgery.

METHODS

Patients 18 years or above who underwent 1-3 level anterior cervical decompression and fusion to address radiculopathy and/or myelopathy at a single institution between 2014 and 2018 with at least 1 year of PROMs were reviewed. Patients were categorized based on cervical deformity into 2 groups: sagittal vertebral axis (cSVA) ≥40 mm as the deformity group, and cSVA <40 mm as the nondeformity group. Patient demographics, surgical parameters, preoperative and postoperative radiographs, and minimum 1-year PROMs were compared.

RESULTS

Of the 230 patients, 191 (83%) were in the nondeformity group and 39 (17%) in the deformity group. Patients with deformity were more likely to be male (69.2% vs. 40.3%, P<0.001) and have a greater body mass index (32.8 vs. 29.7, P=0.028). The deformity group had significantly greater postoperative cSVA (44.2 vs. 25.1 mm, P<0.001) but also had significantly greater ∆cSVA (-4.87 vs. 0.25 mm, P=0.007) than the nondeformity group. Both groups had significant improvements in visual analog scale arm, visual analog scale neck, Short-Form 12 Physical Component Score, and neck disability index (NDI) (P<0.001). However, the deformity group experienced significantly greater ∆NDI and ∆mental component score (MCS)-12 scores (-19.45 vs. -11.11, P=0.027 and 7.68 vs. 1.32, P=0.009).

CONCLUSIONS

Patients with preoperative cervical sagittal deformity experienced relatively greater improvements in NDI and MCS-12 scores than those without preoperative deformity. These results suggest that complete correction of sagittal alignment is not required for patients to achieve significant clinical improvement.

LEVEL OF EVIDENCE

III.

摘要

研究设计

回顾性队列研究。

目的

比较颈椎畸形患者和无畸形患者在接受短节段前路颈椎减压融合术治疗有症状神经根病或脊髓病后的临床结果。

背景资料概要

颈椎畸形越来越被认为是残疾的驱动因素,并与术后患者报告的结果测量(PROMs)更差相关。

方法

对 2014 年至 2018 年间在一家医疗机构接受 1-3 个节段前路颈椎减压融合术治疗神经根病和/或脊髓病的年龄在 18 岁或以上的患者进行回顾性分析。患者根据颈椎畸形分为两组:矢状椎体轴(cSVA)≥40mm 为畸形组,cSVA<40mm 为非畸形组。比较患者的人口统计学资料、手术参数、术前和术后影像学资料以及至少 1 年的 PROMs。

结果

在 230 例患者中,191 例(83%)为非畸形组,39 例(17%)为畸形组。畸形组患者更可能为男性(69.2%比 40.3%,P<0.001)和具有更高的体重指数(32.8 比 29.7,P=0.028)。畸形组术后 cSVA 显著更大(44.2 比 25.1mm,P<0.001),但与非畸形组相比,cSVA 的变化也显著更大(-4.87 比 0.25mm,P=0.007)。两组患者的视觉模拟量表手臂、视觉模拟量表颈部、简短形式 12 项健康调查量表躯体成分评分和颈部残疾指数(NDI)均有显著改善(P<0.001)。然而,畸形组的 NDI 和简短形式 12 项健康调查量表心理成分评分(MCS-12)的变化更大(-19.45 比-11.11,P=0.027 和 7.68 比 1.32,P=0.009)。

结论

术前有颈椎矢状畸形的患者在 NDI 和 MCS-12 评分方面的改善相对更大,而无术前畸形的患者则相对较小。这些结果表明,对于患者而言,完全纠正矢状位排列并非获得显著临床改善所必需的。

证据水平

III 级。

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