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仅行瓣环成形术修复伴有严重反流的均衡性二尖瓣瓣叶脱垂。

Repair with annuloplasty only of balanced bileaflet mitral valve prolapse with severe regurgitation.

机构信息

Department of Cardiac Surgery, Leviev Cardiothoracic and Vascular Center, Sheba Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Department of Cardiothoracic Surgery, Assuta Medical Center, Tel Aviv, Israel.

出版信息

Eur J Cardiothorac Surg. 2022 Mar 24;61(4):908-916. doi: 10.1093/ejcts/ezab548.

Abstract

OBJECTIVES

Repair of severe mitral valve and mitral regurgitation (MR) in patients with degenerative bileaflet pathology can be challenging. Initial results with a ring-only repair (ROR) approach have shown promising results, but long-term outcomes in larger series are lacking. We report on outcomes of ROR in severe MR secondary to bileaflet prolapse, including Barlow's disease.

METHODS

Eighty patients with degenerative multi-segment bileaflet disease underwent ROR for severe MR with a predominantly central regurgitant jet indicating balanced bileaflet prolapse. The main outcome measure of this study was long-term recurrent MR probability. Secondary outcomes were late mortality, reoperation and in-hospital complications.

RESULTS

The mean age was 53 ± 15 years and 54% were males. The mean ejection fraction was 59.2 ± 6.6, 24% and 40% had atrial fibrillation. Barlow's disease was found in 77% of the patients. Minimally invasive surgery was performed in 15 patients (19%). There were no perioperative mortalities or cerebrovascular events in the entire cohort. Post-repair mild outflow tract obstruction (systolic anterior motion) was observed in 4 patients (5%) after ROR. In a mean follow-up of 60 ± 48 months, there was 1 case of death. At follow-up, there was 1 (1%) reoperation due to recurrent MR, and 4 patients who had recurrent moderate or more MR. The 10-year freedom from recurrent MR was 97%. None had severe MR at the latest follow-up.

CONCLUSIONS

In patients with severe MR and a central regurgitant jet secondary to balanced multi-segment bileaflet mitral valve prolapse, ROR is a simple and efficient approach providing excellent long-term results without a substantial risk of systolic anterior motion.

摘要

目的

对于退行性二尖瓣双叶瓣病变伴严重二尖瓣关闭不全(MR)的患者,修复具有挑战性。单纯环修复(ROR)方法的初步结果显示出良好的效果,但缺乏更大系列的长期结果。我们报告了 ROR 治疗因双叶瓣脱垂(包括巴洛氏病)导致的严重 MR 的结果。

方法

80 例退行性多节段二尖瓣双叶瓣病患者因严重 MR 接受 ROR 治疗,主要反流射流呈中心型,提示双叶瓣平衡脱垂。本研究的主要结局测量指标是长期复发性 MR 的概率。次要结局为晚期死亡率、再次手术和住院并发症。

结果

患者平均年龄为 53±15 岁,54%为男性。平均射血分数为 59.2±6.6,24%和 40%有房颤。77%的患者有巴洛氏病。15 例(19%)患者行微创外科手术。整个队列中无围手术期死亡或脑血管事件。ROR 后,4 例(5%)患者出现轻微流出道梗阻(收缩期前向运动)。平均随访 60±48 个月,有 1 例死亡。随访时,有 1 例(1%)因复发性 MR 再次手术,4 例患者出现复发性中度或更严重的 MR。10 年无复发性 MR 率为 97%。随访时,无患者出现严重的 MR。

结论

对于因多节段二尖瓣双叶瓣脱垂伴中心型反流射流导致严重 MR 的患者,ROR 是一种简单有效的方法,提供了出色的长期结果,且不会显著增加收缩期前向运动的风险。

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