非肌层浸润性膀胱癌的整块切除:选择合适的激光
En bloc resection for nonmuscle-invasive bladder cancer: selecting a proper laser.
作者信息
Enikeev Dmitry, Babjuk Marek, Shpikina Anastasia, Shariat Shahrokh, Glybochko Petr
机构信息
Institute for Urology and Reproductive Health, Sechenov University, Moscow, Russia.
Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
出版信息
Curr Opin Urol. 2022 Mar 1;32(2):173-178. doi: 10.1097/MOU.0000000000000968.
PURPOSE OF REVIEW
To discuss the most recent surgical lasers that have been made available to us and to evaluate their potential in performing en bloc resection of nonmuscle invasive bladder cancer.
RECENT FINDINGS
Laser en bloc resection of bladder tumors (ERBT) can be performed with a number of laser systems including Ho:YAG, GreenLight, diode, Tm:YAG and thulium fiber lasers (TFL). The data that is currently available suggests that the water-targeting devices (utilizing water as a primary chromophore - Ho:YAG, Tm:YAG, TFL) may have a number of advantages over hemoglobin-targeting systems (potassium titanyl phosphate:YAG, lithium triborate:YAG). One recent addition to the surgical armamentarium Moses effect enhanced Ho:YAG and the TFL (being able to work both in quasi-continuous and SuperPulsed modes) necessitates careful discussion and comparison with the other available devices.
SUMMARY
The majority of available lasers have proven to be safe to use and compared to electrocautery allow for lower rates of obturator nerve reflex and result in fewer bleeding complications. The minimal penetration depth and decreased peak power of Tm:YAG and TFLs render them the devices of choice when it comes to ERBT. Unfortunately, more studies on ERBT with TFL are needed in order for us to make a sound assessment of the respective pros and cons.
综述目的
讨论现有的最新手术激光设备,并评估其在整块切除非肌层浸润性膀胱癌方面的潜力。
最新发现
膀胱肿瘤激光整块切除术(ERBT)可使用多种激光系统进行,包括钬激光(Ho:YAG)、绿激光(GreenLight)、二极管激光、掺铥钇铝石榴石激光(Tm:YAG)和铥光纤激光(TFL)。目前可得的数据表明,以水为靶点的设备(以水作为主要发色团——钬激光、掺铥钇铝石榴石激光、铥光纤激光)可能比以血红蛋白为靶点的系统(磷酸钛氧钾:YAG、硼酸锂:YAG)具有更多优势。手术器械库中最近新增的摩西效应增强钬激光和铥光纤激光(能够在准连续模式和超脉冲模式下工作)需要与其他现有设备进行仔细讨论和比较。
总结
大多数现有的激光已被证明使用安全,与电灼相比,闭孔神经反射发生率较低,出血并发症较少。掺铥钇铝石榴石激光和铥光纤激光的最小穿透深度和降低的峰值功率使其成为ERBT的首选设备。不幸的是,为了对各自的优缺点做出合理评估,还需要更多关于铥光纤激光用于ERBT的研究。