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估算大流行消退期间的 COVID 风险。

Estimating COVID Risk During a Period of Pandemic Decline.

机构信息

School of Medicine, University of Western Australia, Crawley, WA, Australia.

Marshall Centre for Infectious Diseases, School of Biomedical Sciences, University of Western Australia, Crawley, WA, Australia.

出版信息

Front Public Health. 2021 Dec 17;9:744819. doi: 10.3389/fpubh.2021.744819. eCollection 2021.

Abstract

Many parts of the world that succeeded in suppressing epidemic coronavirus spread in 2020 have been caught out by recent changes in the transmission dynamics of SARS-CoV-2. Australia's early success in suppressing COVID-19 resulted in lengthy periods without community transmission. However, a slow vaccine rollout leaves this geographically isolated population vulnerable to leakage of new variants from quarantine, which requires internal travel restrictions, disruptive lockdowns, contact tracing and testing surges. To assist long term sustainment of limited public health resources, we sought a method of continuous, real-time COVID-19 risk monitoring that could be used to alert non-specialists to the level of epidemic risk on a sub-national scale. After an exploratory data assessment, we selected four COVID-19 metrics used by public health in their periodic threat assessments, applied a business continuity matrix and derived a numeric indicator; the COVID-19 Risk Estimate (CRE), to generate a daily spot CRE, a 3 day net rise and a seven day rolling average. We used open source data updated daily from all Australian states and territories to monitor the CRE for over a year. Upper and lower CRE thresholds were established for the CRE seven day rolling average, corresponding to risk of sustained and potential outbreak propagation, respectively. These CRE thresholds were used in a real-time map of Australian COVID-19 risk estimate distribution by state and territory. The CRE toolkit we developed complements other COVID-19 risk management techniques and provides an early indication of emerging threats to business continuity.

摘要

世界上许多成功控制 2020 年大流行的地区,都被最近 SARS-CoV-2 传播动力学的变化所困扰。澳大利亚在抑制 COVID-19 方面的早期成功导致了长时间没有社区传播。然而,疫苗接种进展缓慢使这个地理位置上孤立的人群容易受到隔离中新变种泄漏的影响,这需要内部旅行限制、破坏性封锁、接触者追踪和检测激增。 为了协助长期维持有限的公共卫生资源,我们寻求一种连续的、实时的 COVID-19 风险监测方法,可以用来提醒非专业人员注意国家级以下的流行风险水平。在进行了探索性数据分析之后,我们选择了公共卫生部门在定期威胁评估中使用的四项 COVID-19 指标,应用业务连续性矩阵并得出一个数字指标;COVID-19 风险估计(CRE),以生成每日实时 CRE、三天净增和七天滚动平均值。我们使用来自澳大利亚所有州和地区的每日更新的开源数据来监测 CRE 超过一年。 为 CRE 的七天滚动平均值设定了上限和下限阈值,分别对应持续和潜在爆发传播的风险。这些 CRE 阈值用于澳大利亚 COVID-19 风险估计分布的实时地图,按州和地区划分。 我们开发的 CRE 工具包补充了其他 COVID-19 风险管理技术,并为业务连续性面临的新威胁提供了早期预警。

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