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姜黄素对肺动脉高压的保护作用。

Protective Effects of Curcumin on Pulmonary Arterial Hypertension.

机构信息

Physiology-Pharmacology Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.

Department of Physiology and Pharmacology, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.

出版信息

Adv Exp Med Biol. 2021;1328:213-221. doi: 10.1007/978-3-030-73234-9_14.

Abstract

Pulmonary hypertension is one of the most common diseases among older people. This disease is usually associated with complications such as vascular changes, vascular remodeling, vasoconstriction, endothelial dysfunction, right ventricular failure, and reduction in nitric oxide availability. Many chemical drugs have been used to treat pulmonary hypertension, but result in limited efficacy and several side effects, and these medications are not always available worldwide. Various studies in traditional medicine have shown that changes in lifestyle and nutritional habits can be extremely effective in both the prevention and treatment of various diseases. One treatment method related to changing nutritional habits is the use of curcumin as a nutritional supplement. Curcumin plays an important role in treating pulmonary hypertension and positively alters the aforementioned complications.

摘要

肺动脉高压是老年人中最常见的疾病之一。这种疾病通常与血管变化、血管重构、血管收缩、内皮功能障碍、右心室衰竭以及一氧化氮供应减少等并发症有关。许多化学药物被用于治疗肺动脉高压,但疗效有限,且有多种副作用,而且这些药物并非在全球范围内都能获得。传统医学的各种研究表明,生活方式和营养习惯的改变对于各种疾病的预防和治疗都非常有效。与改变营养习惯有关的一种治疗方法是使用姜黄素作为营养补充剂。姜黄素在治疗肺动脉高压和积极改变上述并发症方面发挥着重要作用。

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