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水果、果汁和冷冻干燥粉末对炎症性肠病及相关菌群失调的有益作用。

Beneficial Role of Fruits, Their Juices, and Freeze-Dried Powders on Inflammatory Bowel Disease and Related Dysbiosis.

作者信息

Perri Maria Rosaria, Romano Carmen, Marrelli Mariangela, Zicarelli Ludovica, Toma Claudia-Crina, Basta Daniele, Conforti Filomena, Statti Giancarlo

机构信息

Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, CS, Italy.

SIACSA Società Italiana degli Analisti del Comportamento in campo Sperimentale ed Applicativo, 87100 Cosenza, RC, Italy.

出版信息

Plants (Basel). 2021 Dec 21;11(1):4. doi: 10.3390/plants11010004.

Abstract

Inflammatory bowel disease (IBD) is a group of complex chronic inflammatory conditions affecting the gastrointestinal tract. It is linked to a number of genetic and environmental factors able to perturb the immune-microbiome axis. Diet is the most investigated variable both for its role in the etiology of IBD and for its beneficial potential in the treatment of the symptoms. Dietary products may influence intestinal inflammation through different mechanisms of action, such as the modulation of inflammatory mediators, the alteration of gene expression, changes in gut permeability, and modifications in enteric flora composition. A consisting number of studies deal with the link between nutrition and microbial community, and particular attention is paid to plant-based foods. The effects of the dietary intake of different fruits have been investigated so far. This review aims to present the most recent studies concerning the beneficial potential of fruit consumption on human gut microbiota. Investigated plant species are described, and obtained results are presented and discussed in order to provide an overview of both in vitro and in vivo effects of fruits, their juices, and freeze-dried powders.

摘要

炎症性肠病(IBD)是一组影响胃肠道的复杂慢性炎症性疾病。它与许多能够扰乱免疫-微生物群轴的遗传和环境因素有关。饮食因其在IBD病因中的作用及其在治疗症状方面的潜在益处,是研究最多的变量。饮食产品可能通过不同的作用机制影响肠道炎症,如调节炎症介质、改变基因表达、改变肠道通透性以及改变肠道菌群组成。大量研究涉及营养与微生物群落之间的联系,尤其关注植物性食物。迄今为止,已对不同水果的饮食摄入效果进行了研究。本综述旨在介绍有关食用水果对人体肠道微生物群有益潜力的最新研究。描述了所研究的植物种类,并展示和讨论了所得结果,以便概述水果、其果汁和冻干粉的体外和体内效应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e97f/8747592/8dd745a8e423/plants-11-00004-g001.jpg

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