Tseng Hsien-Wei, Chang Po-Ya, Chang Chin-Hao, Wu I-Hui, Hsu Ron-Bin, Chan Chih-Yang
Department of Surgery, Mackay Memorial Hospital, Taitung.
Department of Surgery, National Taiwan University Hospital, Taipei.
J Endovasc Ther. 2023 Feb;30(1):57-65. doi: 10.1177/15266028211068755. Epub 2022 Jan 12.
The purpose of this study was to investigate the change in the diameter of infrarenal abdominal aortic aneurysm (AAA) sacs after endovascular aortic repair (EVAR) in Taiwanese patients and to depict its association with clinical outcomes.
This retrospective cohort study was conducted on patients who underwent EVAR for infrarenal AAA between January 2011 and December 2016. All preoperative and follow-up computed tomography (CT) images were reviewed. Postoperative CT angiography was arranged after 1 month and annually thereafter. The maximal diameter on the axial plane and the maximal diameter perpendicular to the centerline on the coronal and sagittal planes were measured. The study examined post-EVAR sac diameter change over time and compared the differences in adverse events (AEs) among groups.
The survey included a total of 191 patients with a median follow-up duration of 2.5 (interquartile range: 1.1-2.9) years. Overall survival rates at 1, 2, and 5 years were 92%, 81%, and 76%, respectively. According to their last CT scans, the patients were categorized into 3 groups as follows: shrinkage, stationary, and enlargement, which comprised 58 (30.4%), 118 (61.8%), and 15 (7.9%) patients, respectively. Pre-EVAR characteristics and sac diameters were similar among the groups. Sac shrinkage was exclusively observed in the first 2 years, whereas sac enlargement developed at all follow-up periods. Patients with sac enlargement had higher incidence rates of endoleaks, complications, and reintervention than the other groups.
Based on our observations, post-EVAR sac shrinkage only occurs in the first 2 years; however, post-EVAR sacs may enlarge at any point and even after 5 years. In our study, patients with sac enlargement had higher rates of adverse events and reintervention.
本研究旨在调查台湾患者接受血管腔内主动脉修复术(EVAR)后肾下腹主动脉瘤(AAA)瘤腔直径的变化,并描述其与临床结局的关联。
本回顾性队列研究针对2011年1月至2016年12月期间接受肾下AAA的EVAR治疗的患者进行。回顾了所有术前和随访的计算机断层扫描(CT)图像。术后1个月安排CT血管造影,此后每年进行一次。测量轴位平面上的最大直径以及冠状面和矢状面上垂直于中心线的最大直径。本研究考察了EVAR术后瘤腔直径随时间的变化,并比较了各组不良事件(AE)的差异。
该调查共纳入191例患者,中位随访时间为2.5年(四分位间距:1.1 - 2.9年)。1年、2年和5年的总生存率分别为92%、81%和76%。根据他们最后一次CT扫描结果,患者被分为以下3组:缩小组、稳定组和扩大组,分别包括58例(30.4%)、118例(61.8%)和15例(7.9%)患者。各组术前特征和瘤腔直径相似。瘤腔缩小仅在术后前2年观察到,而瘤腔扩大在所有随访期均有发生。瘤腔扩大的患者内漏、并发症和再次干预的发生率高于其他组。
基于我们的观察,EVAR术后瘤腔缩小仅发生在最初2年;然而,EVAR术后瘤腔可能在任何时间点甚至5年后扩大。在我们的研究中,瘤腔扩大的患者不良事件和再次干预的发生率较高。