Petersen Jeffrey, Jhala Darshana
Corporal Michael J Crescenz Veteran Affairs Medical Center (CMCVAMC), Philadelphia, PA, USA.
University of Pennsylvania, Philadelphia, PA, USA.
Clin Pathol. 2022 Jan 7;15:2632010X211068427. doi: 10.1177/2632010X211068427. eCollection 2022 Jan-Dec.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19 disease, has become an international pandemic with numerous casualties. It had been noted that the severity of the COVID-19 disease course depends on several clinical, laboratory, and radiological factors. This has led to risk scoring systems in various populations such as in China, but similar risk scoring systems based on the American veteran population are sparse, particularly with the vulnerable Veteran population. As a simple risk scoring system would be very useful, we propose a simple Jhala Risk Scoring System (JRSS) to assess the severity of disease risk.
A retrospective review of all SARS-CoV-2 reverse transcriptase-polymerase chain reaction (RT-PCR) tests collected and performed at the regional Veterans Administration Medical Center (VAMC) serving the Philadelphia and surrounding areas from March 17th, 2020 to May 20th, 2020. Data was collected and analyzed in the same year. These tests were reviewed within the computerized medical record system for demographic, medical history, laboratory test history, and clinical course. Information from the medical records were then scored based on the criteria of the Jhala Risk Scoring System (JRSS).
The JRSS, based on age, ethnicity, presence of any lung disease, presence of cardiovascular disease, smoking history, and diabetes history with laboratory parameters correlated and predicted (with statistical significance) which patients would be hospitalized.
The JRSS may play a role in informing which COVID-19 positive patients in the emergency room/urgent care for risk stratification.
严重急性呼吸综合征冠状病毒2(SARS-CoV-2)是冠状病毒病(COVID-19)的病原体,已成为造成众多人员伤亡的国际大流行病。已经注意到,COVID-19病程的严重程度取决于多种临床、实验室和放射学因素。这在中国等不同人群中催生了风险评分系统,但基于美国退伍军人人群的类似风险评分系统却很稀少,尤其是针对脆弱的退伍军人人群。由于一个简单的风险评分系统会非常有用,我们提出了一种简单的贾拉风险评分系统(JRSS)来评估疾病风险的严重程度。
对2020年3月17日至2020年5月20日在为费城及周边地区服务的地区退伍军人事务医疗中心(VAMC)收集并进行的所有SARS-CoV-2逆转录聚合酶链反应(RT-PCR)检测进行回顾性研究。同年收集并分析数据。在计算机化病历系统中对这些检测进行审查,以获取人口统计学、病史、实验室检测史和临床病程信息。然后根据贾拉风险评分系统(JRSS)的标准对病历中的信息进行评分。
基于年龄、种族、是否存在任何肺部疾病、是否存在心血管疾病、吸烟史和糖尿病史以及实验室参数的JRSS与哪些患者将住院相关并具有预测性(具有统计学意义)。
JRSS可能有助于在急诊室/紧急护理中对COVID-19阳性患者进行风险分层。