牛白血病的诊断失败：围产期的血清学变化。
Diagnosis failure of bovine leukosis: serology variation during the peripartum period.
机构信息
Department of Animal Production and Preventive Veterinary Medicine, Faculty of Veterinary Medicine and Animal Science, São Paulo State University, Botucatu, SP, Brazil.
Microbiology and Immunology Sector, Instituto Federal Catarinense (IFC), Araquari, Santa Catarina, Brazil.
出版信息
Braz J Microbiol. 2022 Mar;53(1):513-516. doi: 10.1007/s42770-022-00679-4. Epub 2022 Jan 18.
This study demonstrates the influence of pregnancy on serum diagnosis of enzootic bovine leukosis (EBL), emphasizing the importance of routine testing to maintain herd health. For this, 143 pregnant cows were sampled in duplicate (30 days before and 15 days after calving). For EBL diagnosis, samples were submitted to agar gel immunodiffusion testing (AGID). Different results were observed before and after delivery in seventy-six serum samples (53.15%), indicating variations in the levels of serum globulins in the blood during the peripartum period. Therefore, using a single sample for serological diagnosis during the birth season might not represent the correct infection status of animal health due to physiological variations in antibody concentrations.
本研究旨在探讨妊娠对地方性牛白血病（EBL）血清诊断的影响，强调了常规检测对于维持牛群健康的重要性。为此，对 143 头怀孕母牛进行了重复采样（产前 30 天和产后 15 天各采集一份）。采用琼脂凝胶免疫扩散试验（AGID）对 EBL 进行诊断。在 76 份血清样本（53.15%）中观察到分娩前后的结果存在差异，这表明围产期血液中血清球蛋白水平存在变化。因此，在产犊季节使用单个样本进行血清学诊断可能无法反映动物健康的真实感染状态，因为抗体浓度的生理变化会对其产生影响。
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