通过布朗斯特碱组合实现直接C-H羧基化形成多官能化芳族羧酸
Direct C-H Carboxylation Forming Polyfunctionalized Aromatic Carboxylic Acids by Combined Brønsted Bases.
作者信息
Shigeno Masanori, Hanasaka Kazuya, Tohara Itsuki, Izumi Koki, Yamakoshi Hiroyuki, Kwon Eunsang, Nozawa-Kumada Kanako, Kondo Yoshinori
机构信息
Department of Biophysical Chemistry, Graduate School of Pharmaceutical Science, Tohoku University, Aoba, Sendai 980-8578, Japan.
Central Analytical Center, Graduate School of Pharmaceutical Science, Tohoku University, Aoba, Sendai 980-8578, Japan.
出版信息
Org Lett. 2022 Jan 28;24(3):809-814. doi: 10.1021/acs.orglett.1c03866. Epub 2022 Jan 20.
CO fixation into electron-deficient aromatic C-H bonds proceeds with the combined Brønsted bases LiO--Bu and LiO--Am/CsF/18-crown-6 (-Am = CEtMe) under a CO atmosphere to afford a variety of polyfunctionalized aromatic carboxylic acids.
在一氧化碳气氛下，将一氧化碳固定到缺电子的芳香C-H键反应是在布朗斯特碱LiO⁻Bu和LiO⁻Am/CsF/18-冠-6（-Am = CEtMe）的共同作用下进行的，以得到各种多官能化的芳香羧酸。
Zotero 插件