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左肾静脉移植物和原位肝灌注在肝静脉完全侵犯的肝切除术中的应用:血流动力学优化和手术技术。

Left renal vein graft and in situ hepatic perfusion in hepatectomy for complete tumor invasion of hepatic veins: hemodynamic optimization and surgical technique.

机构信息

Department of Surgery, HBP Unit, Virgen de la Arrixaca University Hospital, IMIB-Arrixaca, Murcia, Spain.

Department of Anesthesiology, Virgen de la Arrixaca University Hospital, IMIB, Murcia, Spain.

出版信息

Langenbecks Arch Surg. 2022 Jun;407(4):1-7. doi: 10.1007/s00423-022-02451-6. Epub 2022 Jan 31.

Abstract

PURPOSE

Assessing hepatic vein reconstruction using a left renal vein graft and in situ hypothermic liver perfusion in an extended liver resection.

METHODS

Patients included in this study were those with liver tumors undergoing curative surgery with resection and reconstruction of hepatic veins. Hepatic vein was reconstructed using a left renal vein graft. We describe the technical aspects of liver resection and vascular reconstruction, the key aspects of hemodynamic management, and the use of in situ hypothermic liver preservations during liver transection (prior to and during vascular clamping).

RESULTS

The right hepatic vein was reconstructed with a median left renal venal graft length of 4.5 cm (IQR, 3.1-5.2). Creatinine levels remained within normal limits in the immediate postoperative phase and during follow-up. Median blood loss was 500 ml (IQR, 300-1500) and in situ perfusion with cold ischemia was 67 min (IQR, 60.5-77.5). The grafts remained patent during the follow-up with no signs of thrombosis. No major postoperative complications were observed.

CONCLUSION

Left renal vein graft for the reconstruction of a hepatic vein and in situ hypothermic liver perfusion are feasible during extended liver resection.

摘要

目的

评估在扩大肝切除术中使用左肾静脉移植物和原位低温肝灌注进行肝静脉重建的效果。

方法

本研究纳入了接受根治性手术切除和肝静脉重建的肝肿瘤患者。采用左肾静脉移植物重建肝静脉。我们描述了肝切除术和血管重建的技术方面、血流动力学管理的关键方面,以及在肝切开(在血管夹闭之前和期间)时进行原位低温肝保存的情况。

结果

右肝静脉采用中位长度为 4.5 厘米(IQR,3.1-5.2)的左肾静脉移植物进行重建。术后即刻和随访期间,血肌酐水平均在正常范围内。中位出血量为 500 毫升(IQR,300-1500),原位冷缺血灌注时间为 67 分钟(IQR,60.5-77.5)。移植物在随访期间保持通畅,无血栓形成迹象。未观察到重大术后并发症。

结论

在扩大肝切除术中,使用左肾静脉移植物重建肝静脉和原位低温肝灌注是可行的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8817/9283147/8d4548cadf32/423_2022_2451_Fig1_HTML.jpg

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