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COVID-19 气管切开术的结果。

COVID-19 Tracheostomy Outcomes.

机构信息

Department of Otolaryngology-Head and Neck Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, USA.

Department of Surgery, Baylor College of Medicine, Houston, Texas, USA.

出版信息

Otolaryngol Head Neck Surg. 2022 Dec;167(6):923-928. doi: 10.1177/01945998221075610. Epub 2022 Feb 1.

Abstract

OBJECTIVES

(1) Assess overall COVID-19 mortality in ventilated patients with and without tracheostomy. (2) Determine the impact of tracheostomy on mechanical ventilation duration, overall length of stay (LOS), and intensive care unit (ICU) LOS for patients with COVID-19.

STUDY DESIGN

Case series with planned chart review.

SETTING

Single-institution tertiary care center.

METHODS

Patients with COVID-19 who were ≥18 years old and requiring invasive positive pressure ventilation (IPPV) met inclusion criteria. Patients were stratified into 2 cohorts: IPPV with tracheostomy and IPPV with intubation only. Cohorts were analyzed for the following primary outcome measures: mortality, LOS, ICU LOS, and IPPV duration.

RESULTS

An overall 258 patients with IPPV met inclusion criteria: 46 (18%) with tracheostomy and 212 (82%) without (66% male; median age, 63 years [interquartile range, 18.75]). Average LOS, time in ICU, and time receiving IPPV were longer in the tracheostomy cohort ( < .01). Ability to wean from IPPV was similar between cohorts ( > .05). The number of deaths in the nontracheostomy cohort (54%) was significantly higher than the tracheostomy cohort (29%, < .01).

CONCLUSIONS

While tracheostomy placement in patients with COVID-19 did not shorten overall LOS, mechanical ventilation duration, or ICU LOS, patients with a tracheostomy experienced a significantly lower number of deaths vs those without. One goal for tracheostomy is improved pulmonary toilet with associated shortened IPPV requirements. Our study did not identify this advantage among the COVID-19 population. However, this study demonstrates that the need for tracheostomy in the COVID-19 setting does not portent a poor prognostic factor, as patients with a tracheostomy experienced a significantly higher survival rate than their nontracheostomy counterparts.

摘要

目的

(1)评估有和无气管切开术的机械通气患者的 COVID-19 总死亡率。(2)确定气管切开术对 COVID-19 患者机械通气时间、总住院时间(LOS)和重症监护病房(ICU) LOS 的影响。

研究设计

计划进行病历回顾的病例系列。

设置

单机构三级护理中心。

方法

符合纳入标准的 COVID-19 成年患者,需要有创正压通气(IPPV)。患者分为 2 个队列:气管切开术+IPPV 和仅插管+IPPV。对两组患者进行以下主要结局指标分析:死亡率、LOS、ICU LOS 和 IPPV 时间。

结果

共有 258 名接受 IPPV 的 COVID-19 患者符合纳入标准:46 名(18%)有气管切开术,212 名(82%)没有(66%为男性;中位年龄 63 岁[四分位距 18.75])。气管切开术组的 LOS、入住 ICU 时间和接受 IPPV 时间均较长(<0.01)。两组患者脱机能力相似(>0.05)。无气管切开术组(54%)的死亡人数明显高于气管切开术组(29%,<0.01)。

结论

虽然 COVID-19 患者行气管切开术并未缩短总 LOS、机械通气时间或 ICU LOS,但气管切开术组的死亡率明显低于无气管切开术组。气管切开术的一个目的是改善肺部灌洗,从而缩短 IPPV 需求。本研究在 COVID-19 人群中并未发现这一优势。然而,本研究表明,COVID-19 患者行气管切开术并不预示预后不良因素,因为气管切开术组的生存率明显高于无气管切开术组。

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本文引用的文献

1
Early Outcomes From Early Tracheostomy for Patients With COVID-19.
JAMA Otolaryngol Head Neck Surg. 2021 Mar 1;147(3):239-244. doi: 10.1001/jamaoto.2020.4837.
2
Outcomes After Tracheostomy in COVID-19 Patients.
Ann Surg. 2020 Sep 1;272(3):e181-e186. doi: 10.1097/SLA.0000000000004166.
3
Tracheostomy protocols during COVID-19 pandemic.
Head Neck. 2020 Jun;42(6):1297-1302. doi: 10.1002/hed.26192. Epub 2020 May 2.
4
Chest CT findings of COVID-19 pneumonia by duration of symptoms.
Eur J Radiol. 2020 Jun;127:109009. doi: 10.1016/j.ejrad.2020.109009. Epub 2020 Apr 18.
6
Correlation of Chest CT and RT-PCR Testing for Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases.
Radiology. 2020 Aug;296(2):E32-E40. doi: 10.1148/radiol.2020200642. Epub 2020 Feb 26.
7
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges.
Int J Antimicrob Agents. 2020 Mar;55(3):105924. doi: 10.1016/j.ijantimicag.2020.105924. Epub 2020 Feb 17.
8
Chest CT Findings in Coronavirus Disease-19 (COVID-19): Relationship to Duration of Infection.
Radiology. 2020 Jun;295(3):200463. doi: 10.1148/radiol.2020200463. Epub 2020 Feb 20.
9
To Trach or Not to Trach: Uncertainty in the Care of the Chronically Critically Ill.
Semin Respir Crit Care Med. 2015 Dec;36(6):851-8. doi: 10.1055/s-0035-1564872. Epub 2015 Nov 23.

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