Division of Hepatobiliary Pancreatic Surgery, Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Excellence Center of Organ Transplantation, Faculty of Medicine, Chiang Mai University, Thailand, 110 Intavarorod, Sripoom, 50200, Chiang Mai, Thailand.
BMC Surg. 2022 Feb 11;22(1):48. doi: 10.1186/s12893-022-01507-0.
Pure laparoscopic donor right hepatectomy (PLDRH) can provide better operative outcomes for the donor than conventional open donor right hepatectomy (CODRH). However, the complexity of the procedure typically makes transplant teams reluctant to perform it, especially in low-volume transplant centers. We compared the outcomes of PLDRH and CODRH to demonstrate the feasibility of PLDRH in a low-volume transplant program.
We carried out a retrospective study of adult living donor liver transplantation in Chiang Mai University Hospital from January 2015 to March 2021. The patients were divided into a PLDRH group and a CODRH group. Baseline characteristics, operative parameters, and postoperative complications of donors and recipients were compared between the two groups.
Thirty patients underwent donor hepatectomy between the dates selected (9 PLDRH patients and 21 CODRH patients). The baseline characteristics of the 2 groups were not significantly different. The median graft volume of the PLDRH group was 693.8 mL, which was not significantly different from that of the CODRH group (726.5 mL) The PLDRH group had a longer operative time than the CODRH group, but the difference was not statistically significant (487.5 min vs 425.0 min, p = 0.197). The overall complication rate was not significantly different between the two groups (33.3% vs 22.2%, p = 0.555). Additionally, for the recipients, the incidence of major complications was not significantly different between the groups (71.3 vs 55.6%, p = 0.792).
Even in the context of this low-volume transplant program, whose staff have a high level of experience in minimally invasive hepatobiliary surgery, PLDRH showed similar results to CODRH in terms of perioperative outcomes for donors and recipients.
与传统的开腹右半肝切除术(CODRH)相比,纯腹腔镜供体右半肝切除术(PLDRH)可为供体提供更好的手术结果。然而,该手术的复杂性通常使移植团队不愿意进行该手术,尤其是在低容量移植中心。我们比较了 PLDRH 和 CODRH 的结果,以证明在低容量移植计划中进行 PLDRH 的可行性。
我们对 2015 年 1 月至 2021 年 3 月在清迈大学医院进行的成人活体供肝移植进行了回顾性研究。患者分为 PLDRH 组和 CODRH 组。比较两组供体和受体的基线特征、手术参数和术后并发症。
在选定的日期内有 30 例患者接受了供体肝切除术(9 例 PLDRH 患者和 21 例 CODRH 患者)。两组的基线特征无显著差异。PLDRH 组的供体肝移植体积中位数为 693.8ml,与 CODRH 组(726.5ml)无显著差异。PLDRH 组的手术时间长于 CODRH 组,但差异无统计学意义(487.5min vs 425.0min,p=0.197)。两组的总体并发症发生率无显著差异(33.3%vs 22.2%,p=0.555)。此外,对于受体,两组的主要并发症发生率无显著差异(71.3%vs 55.6%,p=0.792)。
即使在该低容量移植计划中,其工作人员在微创肝胆外科方面具有很高的经验水平,PLDRH 在供体和受体的围手术期结果方面也与 CODRH 相似。