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拉丁美洲营养不良双重负担的挑战与展望。

Challenges and perspectives of the double burden of malnutrition in Latin America.

机构信息

Iberoamerican Nutrition Foundation (FINUT), Av. Del Conocimiento 12, 3.ª pta., Armilla 18016, Granada, Spain.

Iberoamerican Nutrition Foundation (FINUT), Av. Del Conocimiento 12, 3.ª pta., Armilla 18016, Granada, Spain; Department of Nutrition and Food Science, Faculty of Pharmacy, University of Granada, Granada, Spain.

出版信息

Clin Investig Arterioscler. 2022 Jun;34 Suppl 1:S3-S16. doi: 10.1016/j.arteri.2021.11.005. Epub 2022 Feb 10.

Abstract

Nutrition is a key factor in the development of non-communicable chronic diseases (NCCDs), especially cardiovascular diseases (CVD) and their risk factors. The "double burden of malnutrition" (DBM) is the coexistence of undernutrition and overnutrition in the same population across the life-course. In Latin America, the transition from a predominantly underweight to an overweight and obese population has increased more rapidly than in other regions in the world. Undernutrition and the micronutrient deficiencies particularly iron, zinc, and vitamins A and D, present high heterogeneity in Latin American countries, and are currently considered important public health problems. In this region, NCCDs account for 50% of the disability-adjusted life-years, led by CVD. The most prevalent cardiovascular risk factors are overweight, obesity, hypertension, dyslipidemia and type 2 diabetes mellitus. Because of the cost of treatment and the potential years of life lost due to premature death, CVD is known to affect the poorest segments of the population, affecting communities, and governments. More than 80% of CVD deaths occur in low- and middle-income countries. The persistence of damage in some cells due to undernutrition may explain certain findings regarding the increase in NCCD. These aspects together with epigenetic changes have highlighted the importance of a lifelong approach to nutritional policy development. Reducing DBM requires major societal interventions in public health and nutrition to achieve holistic change that can be sustained over the long term and spread throughout the global food system. The implementation of effective state policies of double impact actions should influence both sides of the burden and be considered an urgent priority, considering country-specific inequalities and socio-demographic differences in the Latin American region, using diverse and multidisciplinary strategies.

摘要

营养是导致非传染性慢性病(NCD)发展的关键因素,尤其是心血管疾病(CVD)及其风险因素。“双重营养不足”(DBM)是指同一人群在整个生命过程中同时存在营养不足和营养过剩的情况。在拉丁美洲,超重和肥胖人群的比例从以体重不足为主迅速过渡到以超重和肥胖为主,其增长速度比世界其他地区都快。营养不足和微量营养素缺乏,尤其是铁、锌、维生素 A 和维生素 D,在拉丁美洲国家存在很大的异质性,目前被认为是重要的公共卫生问题。在该地区,NCD 占残疾调整生命年的 50%,其中以 CVD 为主。最常见的心血管危险因素包括超重、肥胖、高血压、血脂异常和 2 型糖尿病。由于治疗费用高昂,以及过早死亡导致的潜在生命损失,CVD 对人口中最贫困的部分造成了影响,影响到社区和政府。超过 80%的 CVD 死亡发生在中低收入国家。由于营养不足导致某些细胞持续受损,这可能可以解释 NCCD 增加的某些发现。这些方面以及表观遗传变化强调了制定营养政策需要采取终身方法的重要性。减少 DBM 需要在公共卫生和营养方面进行重大的社会干预,以实现可以长期持续并在全球粮食系统中传播的整体变革。实施具有双重影响的有效国家政策应同时影响负担的两个方面,并考虑到拉丁美洲地区特定国家的不平等和社会人口差异,利用多样化和多学科的战略。

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