Recurvataside, a new saponin from aerial parts of .

A new glycoside, recurvataside () and six known compounds, quinovic acid (), quinovic acid 28---D-glucopyranosyl ester (), 3---D-glucopyranosylquinovic acid (), 3---D-glucopyranosylquinovic acid 28---D-glucopyranosyl ester (), pomolic acid (), and ursolic acid () were isolated from aerial parts of . The structure of compound was identified from its spectroscopic data and by comparison with the literature. Recurvataside represents the first occurrence of -oleanolic acid saponin bearing two D-glucose units at C-3 and C-28 in nature. This is the first time -oleanane-type saponin reported in the genus . Compounds were evaluated the cytotoxicity against two cancer cell lines MCF-7 and HepG2. Among them, only compound exhibited moderate activity against MCF-7 and HepG2 cell lines with IC value of 16.97 ± 1.55 and 20.28 ± 1.00 μM, respectively. Compounds - were also tested for their inhibitory NO production in LPS-stimulated RAW264.7 cells. Compounds , , and showed significant reduction of nitrite accumulation in LPS-stimulated RAW 264.7 cells with the IC values of 8.81 ± 0.48, 13.42 ± 0.84, and 18.37 ± 0.67 μM, respectively.